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Completed

NCT Number: NCT03753737

Personality Disorders and Substance Use Disorders in a Sexual Context in the Man Having Sex With Other Men Population

Chemsex refers to the use of psychoactive drugs in a sexual context, mainly cathinones, GHB/GBL, methamphetamine, cocaine and ketamine. This can cause infectious or psychiatric complications, addictions, and often goes with high risk sexual behaviours. Recent studies have highlighted the relationship between personality disorders, substance use disorders and risky sexual behaviours. It is important to understand the factors associated with chemsex in order to offer adapted prevention and care plans.

The study hypothesis is that personality disorders, evaluated with the PDQ-4+ questionnaire, are more frequent among man having sex with other men with a substance use disorder linked to chemsex than among man having sex with other men who have never practised chemsex.

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Key information

Conditions

Substance Use Disorders Chemically-Induced Disorders Mental Disorders Substance-Related Disorders

Age range

18 year and older

Sex eligibility

Male

Study type

Observational

Primary location

CSAPA - Service Hépato-gastroentérologie

Lyon, 69004, France

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age over 18
  • Men who have Sex with Men
  • No opposition to participate to the study
  • Chemsex group: to attend an addiction care center for past or present mild, moderate or severe substance-related disorder(s) according to DSM-V criteria, occurring in a sexual context and concerning cathinones, GHB/GBL, methamphetamine, cocaine and/or ketamine.
  • Control group: to consult for a PrEP prescription and never have used cathinones, GHB/GBL, methamphetamine, cocaine or ketamine before or during sex.

Exclusion criteria

  • Deprivation of liberty
  • Guardianship
  • Chemsex group: simple experience of chemsex without substance use disorder

Treatment and study plan

Questionnaires and semi-structured interview

Other
  • Questionnaires : PDQ-4+ (personality disorders), HAD (Anxiety and Depression), AUDIT-c (Alcohol consumption), CTQ-SF (Childhood Trauma Questionnaire).
  • Semi-structured interview : Evaluation of socio-demographic characteristics, psychiatric and addiction comorbidities, sexually transmitted infections, sexual practices, sexual dysfunction, hypersexual disorder.

Primary outcomes

  1. Personality disorders

    Time frame: 1 day

    Positive score for 1 or more DSM-V personality disorders(PD) using French version of the PDQ4+,Personality Diagnostic Questionnaire-Version4,comprising:

    • Combined score of overall personality disturbance (ranges0 to 93);higher values reflect a more important personality disturbance
    • Borderline PD:Score Ranges(SR) 0 to 9,positive(+) if ≥ 5
    • Narcissistic PD:SR 0 to 9,+ if ≥5
    • Histrionic PD:SR 0 to 8,+ if ≥5
    • Antisocial PD:SR 0 to 8,+ if ≥4 and criteria 99 positive
    • Avoidant PD:SR 0 to 7,+ if ≥4
    • Dependent PD:SR 0 to 8,+ if ≥5
    • Obsessive-Compulsive PD:SR 0 to 8,+ if ≥4
    • Paranoid PD:SR 0 to 7,+ if ≥4
    • Schizoid PD:SR 0 to 7,+ if ≥4
    • Schizotypal PD:SR 0 to 9,+ if ≥5
    • Questionnaire must be interpreted with caution if 1 of the 2 "Suspect Questionnaire" items is +, or if at least 2 of the 4 "Too Good" items are +
    • Negativistic and depressive PD are evaluated with the PDQ4+ but are not part of the outcome measures in the study

Sponsors and collaborators

Lead sponsor

Hospices Civils de Lyon

Other

Registry information

Official study title

A Study of the Relationship Between Personality Disorders and Substance Use Disorders in a Sexual Context in the Man Having Sex With Other Men Population - An Observational Study Based on a Cross-sectional Survey.

Acronym: PSYCHEMS

Important dates

Study start
2018
Primary completion
2019
Study completion
2019
First posted
Nov 27, 2018
Registry last updated
May 22, 2019

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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