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Completed

NCT Number: NCT01495429

Peripherally Inserted Versus Centrally Inserted Central Venous Catheters in the Neurological Intensive Care

The investigators aim to compare the complications between centrally and peripherally inserted central venous catheters in neurological intensive care unit patients. The study hypothesis is that peripherally inserted catheters will have more cumulative complications due to venous thrombosis.

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Key information

Conditions

Venous Thrombosis Cardiovascular Diseases Embolism and Thrombosis Thrombosis Vascular Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 3

Primary location

University of Michigan Health System, Ann Arbor, Michigan, United States

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Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • all patients age > 18, admitted to the neurological ICU who are require a de novo central venous catheter as standard of care and in which a double lumen 5f PICC or CICVC (triple lumen, 7f) are acceptable for the indication.
  • the patients must be expected to survive and need a central venous catheter for at least 7 days.

Exclusion criteria

  • prisoner
  • age < 18
  • expected to die or have care withdrawn prior to ICU day 7
  • requiring an emergent central venous catheter
  • suspected bacteremia
  • recent central venous catheter within the last 30 days
  • patients who are not a candidate for bedside placement of either a CICVC or PICC line
  • patients with renal insufficiency with creatinine level greater than 3.0 mg/dL (265.2 m mol/L) or who were undergoing hemodialysis
  • patients requiring a central venous catheter for prolonged antibiotic therapy\\
  • patient who the treating clinician feels clearly needs one particular type of catheter over the other

Treatment and study plan

Central venous catheter

Procedure

Placement of a peripherally inserted central venous catheter

Primary outcomes

  1. The composite of death or catheter related large vein thrombosis

    Time frame: 15 days

Secondary outcomes

  1. Cumulative catheter related complications until discharge

    Time frame: 30 days

Sponsors and collaborators

Lead sponsor

University of Michigan

Other

Registry information

Official study title

A Phase III Study of Peripherally Inserted Versus Centrally Inserted Central Venous Catheters in the Neurological Intensive Care Unit

Acronym: PICNIC

Important dates

Study start
2012
Primary completion
2015
Study completion
2015
First posted
Dec 20, 2011
Registry last updated
Aug 4, 2015

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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