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OpenTrials
Completed

NCT Number: NCT03007355

Peripheral Perfusion Index (PPI) as Monitor During Deliberate Hypotensive Anesthesia

Hypotensive anesthesia is effective in reducing the intraoperative blood loss. The risk of hypoperfusion of vital organs continues to be a concern. An adequate monitoring of tissue perfusion and oxygenation is crucial issue. Peripheral Perfusion Index (PPI) as a noninvasive new monitoring, can reflect the peripheral perfusion dynamics.

This study is designed to explore the behaviour and trend of PPI during nitroglycerine induced deliberate hypotensive anesthesia in adult patients undergoing functional endoscopic sinus surgery (FESS).

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Key information

Conditions

Monitoring During Deliberate Hypotensive Anesthesia

Age range

18 year–50 year

Sex eligibility

All sexes

Study type

Observational

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients, aged from 18-50 years, ASA physical status I and II, undergoing functional endoscopic sinus surgery (FESS) under deliberate hypotensive anesthesia

Exclusion criteria

  • Patients with systemic hypertension, cardiovascular disease, cerebrovascular insufficiency, coagulation defects, renal or hepatic insufficiency, and hypersensitivity to the study drugs will be excluded from the study. Patients receiving vasoactive drugs or beta blockers will be also excluded from the study.

Treatment and study plan

peripheral perfusion index measurement

Other

Primary outcomes

  1. correlation between PPI and T1

    Time frame: start of nitroglyceirn infusion till target arterial pressure is reached up to 2 hours

    correlation of baseline values of PPI and time required to achieve target mean arterial pressure.

Sponsors and collaborators

Lead sponsor

Cairo University

Other

Registry information

Official study title

The Use of Peripheral Perfusion Index as a Predictor for Patient's Response to Deliberate Hypotension During Functional Endoscopic Sinus Surgery A Prospective Observational Study

Acronym: PPI

Important dates

Study start
2017
Primary completion
2017
Study completion
2017
First posted
Jan 2, 2017
Registry last updated
Dec 19, 2018

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.