Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán
Mexico City, D.f., Mexico, 14000, Mexico
NCT Number: NCT02264509
The purpose of this study is to determine the risk factors associated with the occurrence of arterial insufficiency in patients with HIV / AIDS, and to identify the prevalence of this disease. The estimated prevalence is 10%, similar to that reported in the general population.
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Notify Me18 year–89 year
All sexes
Observational
Mexico City, D.f., Mexico, 14000, Mexico
A case study nested in a cohort of patients with HIV / AIDS at Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico, with a cohort of 1500 patients , a sample size of 206 individuals was calculated. Data collection was performed in a prospective cross shape.
During the interview, written informed consent for inclusion in the study, along with a standard query of vascular surgery in which the patient's history as well as cardiovascular risk factors. Also, a vascular physical examination including palpation of pulses in upper and lower extremities (brachial, radial, ulnar, femoral, popliteal, posterior tibial and dorsalis pedis), femoral murmurs search and determining ankle / brachial indexes with a standardized method.
In determining the ABI was counted with a Doppler ultrasound 8 mHz, transducer gel and a sleeve for manual measurement of blood pressure, 20% longer than the largest diameter of the arm circumference.
If the patient is diagnosed with, symptomatic or asymptomatic arterial insufficiency, ABI measurements were performed at rest and effort, plus pressure index finger-arm or plethysmography. Patients with altered rates were followed in vascular surgery care.
The data were recorded in a single database unique protected by password. The results were analyzed using the statistical program STATA v 9.0.
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
The only procedure to be performed is the measurement of ABI for the diagnosis of arterial insufficiency.
Time frame: 1 time
Arterial insufficiency is measured by Ankle / brachial index described as ABI<0.9 or ABI >1.2
Time frame: 1 time
Male or Female
Time frame: 1 time
Number of years
Time frame: 1 time
Defined as diagnosis in previous notes in the file or use of oral hypoglycemic agents.
Time frame: 1 time
Defined as the last digit of C-LDL in serum of the patient, which is more than 150 mg / dL.
Time frame: 1 time
Defined as the last digit of the patient's serum triglycerides, which is greater than 200 mg / dL.
Time frame: 1 time
Defined as the last digit of HDL-C in patient serum, which is less than 50 mg / dL.
Time frame: 1 time
Defined as diagnosis in previous notes or use of antihypertensives.
Time frame: 1 time
Defined as previous heart attack.
Time frame: 1 time
Defined as previous diagnosis in the record.
Time frame: 1 time
Smoking yes or no.
Time frame: 1 time
Smoking index defined as the number of cigarettes smoked per day by the number of years of smoking divided by 20.
Time frame: 1 time
Defined as use or history of use of drugs of abuse investigated during the interview
Time frame: 1 time
Defined as confirmatory serologic diagnosis of HIV associated with AIDS-defining illnesses
Time frame: 1 time
Defined as the time interval in months from diagnosis of HIV to interview for the research protocol.
Time frame: 1 time
Defined as the last number of copies of certain virus in patient serum in the record.
Time frame: 1 time
Defined as the final determination of number of CD4 in serum.
Time frame: 1 time
Defined as use of at least one drug with anti-retroviral activity.
Time frame: 1 TIME
Defined as a period in months
Time frame: 1 time
Defined as confirmatory serological diagnosis of HIV (ELISA + Western Blot)
Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
Other
Prevalence and Risk Factors of Arterial Insufficiency in Patients With HIV / AIDS
Acronym: AIHIV
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View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
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