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NCT Number: NCT05292235

Perioperative Parameter and Treatment Outcomes of Surgical Treatment for Benign Prostate Hyperplasia in Hong Kong

This is a prospective data registry to assess the treatment outcomes and complications of different treatment approaches in our hospital clusters.

Recruiting

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Key information

Age range

18 year and older

Sex eligibility

Male

Study type

Observational

Primary location

Alice Ho Miu Ling Nethersole Hospital, Hong Kong

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About this study

Benign prostatic hyperplasia (BPH) is a very common disease affecting men. Patients with BPH may present with voiding symptoms including hesitancy, intermittence, slow stream and sensation of incomplete emptying, and storage symptoms including urinary frequency, urgency and nocturia. Patients may also suffer from complications including urinary retention, recurrent urinary tract infection, bladder stone formation and obstructive uropathy. For patients who have lower urinary tract symptoms refractory to medications, or those who suffer from complications of BPH, transurethral prostatectomy should be considered.

Surgical intervention options have evolved from electrosurgical resection to the use of lasers for enucleation and ablation [1]. Aquablation and Rezum system are new minimally invasive surgical technology for BPH management. [2,3,4]. Different treatment approaches will result in different treatment successful rate and also potential adverse effects to patients.

However, large-scale studies investigating the different modalities of surgical treatment of BPH are lacking. Therefore, a prospective data registry is created to assess the perioperative surgical outcomes for different surgical treatment of BPH.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patient at the age of 18 or above

Exclusion criteria

  • Patient is unable to give consent

Treatment and study plan

Primary outcomes

  1. International Prostate Symptom Score (IPSS) questionnaire total Score

    Time frame: Baseline, 3 months after surgical treatment for BPH

    Change in total scores in International Prostate Symptom Score (ranges from 0 to 35) questionnaires

  2. Voiding function in uroflowmetry

    Time frame: Baseline, 3 months after after surgical treatment for BPH

    Change in urodynamic function assessed by Uroflowmetry

Secondary outcomes

  1. Complication after surgical treatment

    Time frame: Post operation 30 days after surgical treatment for BPH

    The 30-day complications will be graded according to the Clavien-Dindo classification

Study contacts

Contact information is provided by the study sponsor or research team.

Chi Fai NG, MD

CONTACT

[email protected]

35052625

Sponsors and collaborators

Lead sponsor

Chinese University of Hong Kong

Other

Registry information

Official study title

A Prospective Assessment of the Perioperative Parameter and Treatment Outcomes of Surgical Treatment for Benign Prostate Hyperplasia in Hong Kong

Important dates

Study start
2022
Primary completion
2032
Study completion
2032
First posted
Mar 23, 2022
Registry last updated
May 6, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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