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OpenTrials
Completed

NCT Number: NCT05384795

Perioperative Atelectasis in Orthopaedic Surgery: a Prospective Study

This study aims at comparing a perioperative pulmonary atelectasis score, measured by pulmonary ultrasound, in patients operated undergoing orthopedic surgery under general anesthesia, spinal anesthesia or peripheral nerve block. The association between the atelectasis score and previously identified risk factors will be studied.

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Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Centre Hospitalier Universitaire Vaudois

Lausanne, Canton of Vaud, 1005, Switzerland

About this study

Atelectasis is one of the most common pulmonary complications in the perioperative period, occurring in 85% to 90% of patients under general anesthesia. It can be responsible for hypoxemia and be associated with postoperative pulmonary complications such as pneumonia. The consequences are a prolongation of the hospital stay and an increase in mortality.

The appearance of perioperative atelectasis is mainly secondary to the induction of general anesthesia with an incidence up to 90%. The different causes are, for example, the administration of muscle relaxants, mechanical ventilation and the position of the patient.

In orthopedic surgery, many procedures are performed under spinal anesthesia or under peripheral nerve block. At present, there are no studies measuring the incidence of atelectasis in patients operated under these two techniques of locoregional anesthesia, with the exception of parturients undergoing cesarean section.

This study aims at comparing a perioperative pulmonary atelectasis score, measured by pulmonary ultrasound, in patients operated undergoing orthopedic surgery under general anesthesia, spinal anesthesia or peripheral nerve block. The association between the atelectasis score and previously identified risk factors will be studied.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients over the age of 18;
  • Patients scheduled for an elective operation at the Orthopedic Hospital of CHUV;
  • Signature of the study consent

Exclusion criteria

  • Thoracic deformities preventing the performance of pulmonary ultrasound (dressings, drains, fractures, etc.);
  • Refusal to participate;
  • Patient does not speak French.
  • Inability to discern

Treatment and study plan

Lung ultrasound

Other

Lung atelectasis score

Primary outcomes

  1. Lung atelectasis score

    Time frame: immediately after the surgery

    Atelectasis score based on validated ultrasound quantification (comparing different anesthesia techniques)

Secondary outcomes

  1. Lung atelectasis score

    Time frame: Four timepoints: at baseline, immediatly before surgery (after anesthesia induction), immediately after the surgery, and at the recovery room

    Atelectasis score

Sponsors and collaborators

Lead sponsor

Eric Albrecht

Other

Registry information

Official study title

Perioperative Atelectasis in Patients Undergoing Orthopaedic Surgery: Prospective Cohort Study

Acronym: ATELHO

Important dates

Study start
2022
Primary completion
2022
Study completion
2022
First posted
May 20, 2022
Registry last updated
Apr 5, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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