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OpenTrials
Completed

NCT Number: NCT06521203

Periapical Lesions and Immediate Implants

The aim of this case-control study is to evaluate the success and survival rates of dental implants immediately placed into extraction sites in the presence of periapical pathology.

The main questions it aims to answer are:

What were the survival and success rates of implants immediately placed into extraction sockets of teeth with chronic periodical lesions.

A retrospective analysis was performed based on the evaluation of certain clinical and radiographic parameters 12 months after prosthetic function of these implants.

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Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Akdeniz University

Antalya, 07070, Turkey (Türkiye)

About this study

In 25 patients (13 men, 12 women), certain clinical and radiological parameters were retrospectively evaluated with particular interest in survival and success rates of the implants (total of 30 implants, 21 in the maxilla, 9 in the mandible) placed immediately to extraction sites of teeth with chronic periapical lesions. These parameters included mobility and the presence or absence of chronic pain, probing depth, gingival index, radiographic measurements of crestal bone loss on mesial and distal aspects of the implants.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • To have 1 or more teeth with a chronic periapical lesion that requiring extraction.
  • The chronic periapical lesion should be determined as an asymptomatic periapical radiolucency with a diameter ranging between 4 and 8 mm.
  • The patients undergoing tooth extraction must have been treated with an immediate implant placement procedure.
  • At the time of extraction and implant placement, the neighboring teeth must have had healthy periodontal and periapical status.

Exclusion criteria

  • Age younger than 18 years
  • Any systemic disease or medication that might compromise osseointegration, bone or soft tissue healing
  • Smoking
  • Purulent exudate during the extraction
  • Severe deficiency of soft and/or hard tissue in implant region
  • Pregnancy
  • Lactation
  • History of chemotherapy or radiotherapy
  • Severe parafunctional habits

Treatment and study plan

Primary outcomes

  1. Survival of the implants

    Time frame: Immediately after the implant placement and after 12 months of prosthesis function.

    Pain on palpation, percussion, or function (Yes/No) Implant mobility (Yes/No) Radiographic crestal bone loss (<4.0 mm) Absence of pain and mobility and crestal bone loss up to 4 mm were regarded as survive.

  2. Success of the implants

    Time frame: Immediately after the implant placement and after 12 months of prosthesis function.

    Pain on palpation, percussion, or function (Yes/No) Implant mobility (Yes/No) Radiographic crestal bone loss (<2mm) Gingival index score (1-2-3) Probing depth (mm) Absence of pain and mobility, crestal bone loss <2mm, GI score less than 2, probing depth <5mm were regarded as success.

Sponsors and collaborators

Lead sponsor

Akdeniz University

Other

Registry information

Official study title

Immediate Implant Placement in Sites With Chronic Periapical Lesions

Important dates

Study start
2016
Primary completion
2018
Study completion
2023
First posted
Jul 25, 2024
Registry last updated
Jul 25, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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