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NCT Number: NCT06092008

Performance of New Diagnostic Methods in Older Adults With Pneumonia

Create a clinical diagnostic pathway for older ED adults with pneumonia and its subgroups (bacterial, viral, and co-infection) and determine whether novel biomarkers improve diagnostic accuracy. The investigators will conduct a prospective observational trial of 250 ED patients ≥65 years old with suspected pneumonia. The investigators will perform analyses overall and by subgroups, seeking common models to ease adoption.

Recruiting

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Key information

Conditions

Pneumonia Infections Lung Diseases Respiratory Tract Diseases Respiratory Tract Infections

Age range

65 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

The Ohio State University

Columbus, Ohio, 43210, United States

Location status: Recruiting

Location contact

Katherine Buck, MD, MPH

CONTACT

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Adults aged 65 and older presenting to the ED with suspected pneumonia defined as (1) either a physician order for CXR OR CT OR a chief complaint consistent with dyspnea; AND (2) physician suspicion of pneumonia prior to ED testing (score of 2-5 on Likert scale)

Exclusion criteria

  • inability to obtain consent from the patient or an LAR
  • active cancer
  • organ transplant
  • immunosuppression
  • trauma activation
  • suicidal ideation
  • incarceration
  • antibiotics in the last 14 days
  • a separate episode of lower respiratory illness in the last 30 days

Treatment and study plan

Primary outcomes

  1. Pneumonia

    Time frame: 3 years

    Presence or absence of pneumonia based on adjudicator review of chart. The goal of the study is to create a diagnostic pathway for pneumonia in older adult emergency department patients.

Study contacts

Contact information is provided by the study sponsor or research team.

Michael Hill, RN

CONTACT

[email protected]

614-293-6185

Sponsors and collaborators

Lead sponsor

Ohio State University

Other

Registry information

Official study title

Establishing and Implementing Pneumonia Diagnosis in ED Older Adults: A Mixed Methods Approach

Acronym: PNEUMO

Important dates

Study start
2022
Primary completion
2026
Study completion
2027
First posted
Oct 23, 2023
Registry last updated
Feb 6, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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