Percutaneous Robotic Navigation Microwave Ablation Versus CT-guided Microwave Ablation in the Treatment of Pulmonary Nodules With Ground-glass Opacity

Inclusion criteria

• Aged 18 to 85 years
• Nodules measuring 3-30mm with ground-glass opacities constituting ≥75% of the lesion
• Preoperative clinical evaluation confirming no hilar or mediastinal lymph node metastasis and no distant metastasis
• Patients diagnosed as stage IA primary peripheral lung cancer according to the UICC 8th TNM staging system, and with one of the following conditions:

(i) cannot undergo surgical resection due to poor cardiopulmonary function or advanced age (ii) refusing or unwilling to undergo surgical resection (iii) with newly developed or residual pulmonary nodules after early-stage primary lung cancer surgery (iv) with unilateral lung disease who cannot undergo unilateral surgical resection (v)with multiple primary lung cancers unsuitable for surgical resection

• Preoperative ECOG physical status score is 0/1
• ASA score is I-III
• Patients voluntarily participate in this study and sign the informed consent form

Exclusion criteria

• Smoking cessation duration <2 weeks
• Lesions adjacent to pulmonary artery-vein main trunks
• Lesions near the hilum or adjacent to lobar bronchi
• Pregnancy or lactation status
• Severe mental disorders
• History of other malignancies within 5 years
• Unstable angina or myocardial infarction within 6 months with coronary angiography showing severe stenosis of major coronary branches
• Cerebral infarction or hemorrhage within 6 months
• Continuous systemic corticosteroid therapy within 1 month
• Patients or their authorized persons who do not wish to comply with the study protocol
• Patients with other investigator-assessed ineligibility for the trial