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OpenTrials
Completed

NCT Number: NCT01847209

Percutaneous Image Guided Video-Assisted Thoracic Surgery (VATS) Resection of Lung Lesions

This is a phase II protocol to determine the safety and feasibility of Intraoperative CT fluoroscopy guidance for lung resection for small nodules.

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Key information

Conditions

Lung Cancer Lung Diseases Lung Neoplasms Neoplasms Neoplasms by Site Respiratory Tract Diseases Respiratory Tract Neoplasms Thoracic Neoplasms

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 2

Primary location

Brigham and Women's Hospital

Boston, Massachusetts, 02115, United States

About this study

This is a phase II protocol to determine the safety and feasibility of image guided CT marking for resection of small lung nodules. This is relevant because many such nodules are hard to localize for minimally invasive lung resection. It is hoped that this technology using fluoro CT capability available now in most operating room will improve safety and reliability of thoracic surgery.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • peripheral lung nodules < 3cm in size
  • Surgical candidate

Exclusion criteria

  • Non surgical candidate

Treatment and study plan

Video-Assisted Thoracic Surgery (VATS) wedge resection

Procedure

Other names: Nodules marked with fiducials such as Kopan needles under CT fluoroscopy followed by VATS wedge resection.

Primary outcomes

  1. Number of Participants With Treatment-related Adverse Events as Assessed by CTCAE v4.0

    Time frame: 30 days

    The patient will be monitored while in the hospital by their thoracic surgical team as well as by two research nurses named Lauren Donahue, RN and Karen Magsipoc, NP. The research nurses will document any perioperative complications and mortality that arise during the patient's stay in the hospital.

Secondary outcomes

  1. Patients Underwent a Successful Resection

    Time frame: 30 days

    Number of patients who underwent a successful resection which is measured by an accurate and appropriate resection in a given timeline

Sponsors and collaborators

Lead sponsor

Brigham and Women's Hospital

Other

Collaborators

  • Siemens Medical Solutions USA - CSG

Registry information

Official study title

Percutaneous Image Guided Video Assisted Thoracic Surgery (VATS) Resection of Lung Lesions

Important dates

Study start
2013
Primary completion
2017
Study completion
2017
First posted
May 6, 2013
Registry last updated
Nov 18, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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