Skip to main content
OpenTrials
Recruiting

NCT Number: NCT05693857

Perceive and Calculated CV Risk

Cardiovascular prevention guidelines use estimated 10-year atherosclerotic cardiovascular disease (ASCVD) risk to guide treatment decisions and engage patients in shared decision-making. Research has focused on refining the accuracy of these CV risk calculators for different populations, relatively little has been done to understand how patients perceive their own ASCVD risk. Accurate perception of a patient's risk by both the patient and the doctors is important because this is an important determinant of health-related behaviour. Patients often show optimistic bias when considering their own CV risk and consistently underestimate it.

We aim to determine patient perceived versus actual risk of ASCVD in a Chinese population. We aim to better understand the degree to which patients underestimate or overestimate their ASCVD risk and whether patients are better or worse at estimating their ASCVD risk relative to their peers of the same age and sex. Finally, we aim to evaluate patients willingness to follow guideline recommended CV prevention and specifically lipid-lowering therapy.

Recruiting

Interested in participating?

Request Info

Key information

Age range

40 year–90 year

Sex eligibility

All sexes

Study type

Observational

Primary location

The Chinese University of Hong Kong

Shatin, 999077, Hong Kong

Location status: Recruiting

Location contact

Daniel Xu

CONTACT

[email protected]

35051518 ext. 1518

About this study

Cardiovascular prevention guidelines use estimated 10-year atherosclerotic cardiovascular disease (ASCVD) risk to guide treatment decisions and engage patients in shared decision-making. Research has focused on refining the accuracy of these CV risk calculators for different populations, relatively little has been done to understand how patients perceive their own ASCVD risk. Accurate perception of a patient's risk by both the patient and the doctors is important because this is an important determinant of health-related behaviour. Patients often show optimistic bias when considering their own CV risk and consistently underestimate it.

We aim to determine patient perceived versus actual risk of ASCVD in a Chinese population. We aim to better understand the degree to which patients underestimate or overestimate their ASCVD risk and whether patients are better or worse at estimating their ASCVD risk relative to their peers of the same age and sex. Finally, we aim to evaluate patients willingness to follow guideline recommended CV prevention and specifically lipid-lowering therapy.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Aged 40 years and above
  • Consent to complete questionnaire
  • Lipid profile within 12 months

Exclusion criteria

  • Known ASCVD defined as history of coronary heart disease (i.e. obstructive coronary disease, prior myocardial infarction, or prior coronary revascularization); cerebrovascular disease (i.e. stroke or transient ischemic attack); and peripheral arterial disease (i.e. obstructive peripheral disease, prior vascular amputation or prior revascularization)
  • Other chronic illness with life-expectancy <12 months

Treatment and study plan

Cardiovascular prevention guidelines

Other

Cardiovascular prevention guidelines use estimated 10-year atherosclerotic cardiovascular disease (ASCVD) risk to guide treatment decisions and engage patients in shared decision-making

Primary outcomes

  1. Evaluate correlation between patients' own estimates of their 10-year risk of heart disease or stroke with actual pooled-cohort-equation calculated risk estimates (using a validated CV risk calculation app).

    Time frame: 12-months

Secondary outcomes

  1. Evaluate correlation between perceived and calculated 10-year CV risk in sub-groups based on age, sex, education level, known CV risks (e.g. smoking, diabetes, hyperlipidemia and hypertension

    Time frame: 12-months

  2. Evaluate patients' own estimates of 10-year CV risk relative to their peers using age- and sex-specific population risk percentiles.

    Time frame: 12-months

  3. Evaluate patients' willingness to follow recommendations for CV prevention based on their calculated 10-year CV risk profile (e.g. dietary, exercise, smoking and CV risk factor control)

    Time frame: 12-months

  4. Evaluate whether perceived or actual CVD risk is associated with current statin use or willingness to take statin.

    Time frame: 12-months

  5. Reasons for unwillingness to follow recommendations for CV preventions

    Time frame: 12-months

  6. Source of CV health information and advice

    Time frame: 12-months

Study contacts

Contact information is provided by the study sponsor or research team.

Daniel Xu

CONTACT

[email protected]

35051518

Sponsors and collaborators

Lead sponsor

Chinese University of Hong Kong

Other

Collaborators

  • Gormin Tan gtan

Registry information

Official study title

Patient-Perceived Versus Actual Risk of Cardiovascular Disease and Willingness to Follow Recommendations for Cardiovascular Prevention

Important dates

Study start
2023
Primary completion
2028
Study completion
2028
First posted
Jan 23, 2023
Registry last updated
Feb 16, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.