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Completed

NCT Number: NCT03490305

Penetrating Abdominal Injuries From the Battle of Mosul

The battle of Mosul was characterized by the use of improvised explosive devices, human shields and suicide bombers in an urban setting. It is unclear whether this type of warfare cause more extensive abdominal injuries to civilians than combatants. All patients admitted with penetrating abdominal injury subjected to an exploratory laparotomy at Emergency Hospital, Erbil, between October 17, 2016 and July 16, 2017 will be included. Differences in demographics, injury mechanism, time since injury, clinical status on arrival, intraoperative findings, postoperative complications and outcome will be studied.

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Key information

Sex eligibility

All sexes

Study type

Observational

Primary location

Emergency Hospital

Erbil, Kurdistan, Iraq

About this study

Study Rationale The battle of Mosul was characterized by the use of improvised explosive devices, human shields and suicide bombers in an urban setting. It is unclear whether this type of warfare cause more extensive abdominal injuries to civilians than combatants. Understanding of the correlation between the severity of abdominal injuries, type of warfare and population affected is of importance when planning for surgical care in a conflict setting.

Aim To assess whether civilians obtain more extensive abdominal injuries than combatants in an urban battle characterized by the use of indiscriminate weapons.

Study Design An observational retrospective cohort study with longitudinal data collection.

All patients admitted with penetrating abdominal injury subjected to an exploratory laparotomy at Emergency Hospital, Erbil, between October 17, 2016 and July 16, 2017 will be included. Differences in demographics, injury mechanism, time since injury, clinical status on arrival, intraoperative findings, postoperative complications and outcome will be analysed.

Primary Objective Differences in injury mechanism, organs injured, surgical treatment given, postoperative complications and outcome between civilians and combatants.

Secondary Objectives Differences in surgical treatment given, postoperative complications and outcome between patients with prior surgical treatment of their injury and patients without prior surgical treatment.

Differences in surgical treatment given, postoperative complications and outcome between patients who receive surgical treatment less than 24 hours from injury and patients who receive surgical treatment more than 24 hours from injury will be analysed.

Statistical methods Differences between groups will be analysed using t-test and regression models.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

(all must be fulfilled):

  • Penetrating abdominal injury
  • Subjected to an exploratory laparotomy at Emergency Hospital, Erbil, Iraq
  • Between October 17, 2016 and July 16, 2017

Exclusion criteria

(all must be fulfilled):

  • Patients who received treatment several times will only be counted as one patient
  • Between October 17, 2016 and July 16, 2017

Treatment and study plan

Exploratory laparotomy

Procedure

Findings and procedures done at exploratory laparotomy

Primary outcomes

  1. Differences in injury mechanism, organs injured, surgical treatment given, postoperative complications and outcome between civilians and combatants.

    Time frame: an average of 3 weeks

Secondary outcomes

  1. Differences in surgical treatment given, postoperative complications and outcome between patients with prior surgical treatment of their injury and patients without prior surgical treatment.

    Time frame: an average of 3 weeks

  2. Differences in surgical treatment given, postoperative complications and outcome between patients who receive surgical treatment less than 24 hours from injury and patients who receive surgical treatment more than 24 hours from injury will be analysed.

    Time frame: an average of 3 weeks

Sponsors and collaborators

Lead sponsor

Vrinnevi Hospital

Other

Collaborators

  • Center for Disaster Medicine and Traumatology, Linköping University
  • Emergency Hospital, Erbil, Iraq
  • Karolinska Institutet

Registry information

Official study title

Exploratory Laparotomy Following Penetrating Abdominal Injuries From the Battle of Mosul: a Cohort Study From a Referral Hospital in Erbil, Kurdistan Region in Iraq

Acronym: Exlap

Important dates

Study start
2017
Primary completion
2018
Study completion
2018
First posted
Apr 6, 2018
Registry last updated
Oct 16, 2018

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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