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NCT Number: NCT05700994

Peer Engagement in Methamphetamine Harm-Reduction With Contingency Management (PEER-CM)

The main goal of this study is to tests the effect of incentivizing achievement of self-identified, personal harm reduction goals (Contingency management or CM) compared with standard of care (peer harm reduction service with incentives for peer visits) to increase the reach and effectiveness of methamphetamine (MA) harm reduction services.

Active, Not Recruiting

This study is active but is not currently recruiting participants.

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Key information

Age range

18 year–105 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Comagine Health, Portland, Oregon, United States

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About this study

Using a hybrid type 1 effectiveness-implementation framework and stepped-wedge design, this study will randomize eighteen community-based peer harm reduction sites to provide contingency management incentives for achieving self-identified harm reduction goals set with peer specialists using a participant-driven harm reduction goal-setting process (e.g. completing overdose prevention and supply training, daily life goals, treatment and care goals, relationship and social support goals) versus standard of care contingency management (i.e. incentives for peer encounter attendance).

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

This intervention is at the site level. Community-based organization sites are eligible if they:

  • Use peer support specialists to provide direct outreach and harm reduction services to people who use drugs
  • Are willing to be trained in the two strategies for peer-facilitated contingency management

Clients who:

  • Age 18 and older
  • Any stimulant (methamphetamine, cocaine) use in the past 30 days
  • Willing to accept peer services
  • Willing to complete initial and follow-up assessments with peer
  • Able to communicate in English or Spanish

Exclusion criteria

Community-based organization sites who:

  • Do not use peer support specialists to provide direct outreach and harm reduction services to people who use drugs
  • Are not willing to be trained in the two strategies for peer-facilitated contingency management

Clients who:

  • Present any danger or threat of violence to peers

Treatment and study plan

Peer Contingency Management

Behavioral

Participants allocated to peer-facilitated contingency management will receive incentives for achieving self-identified harm reduction goals set with peer specialists using a participant-driven harm reduction goal-setting process (e.g. completing overdose prevention and supply training, daily life goals, treatment and care goals, relationship and social support goals)

Other names: PEER-CM

Standard of Care Contingency Management

Behavioral

Participants allocated to standard of care contingency management will receive incentives for peer encounters.

Other names: Standard of Care

Primary outcomes

  1. Number of participants who overdose

    Time frame: 6 months from baseline

    Test the impact of incentives for achieving self-identified, personal harm reduction goals on the likelihood of overdose among people using methamphetamine at 6 months from enrollment identified through completed assessment.

  2. Number of participants who achieve self-identified goals

    Time frame: 6 months from baseline

    Determine whether incentives for achieving self-identified, personal harm reduction goals increases engagement with harm reduction services at 6 months from enrollment identified through completed assessment.

  3. Number of participants who engage in substance use disorder treatment

    Time frame: 6 months from baseline

    Determine whether incentives for achieving self-identified, personal harm reduction goals increases engagement with treatment services at 6 months from enrollment identified through completed assessment.

Sponsors and collaborators

Lead sponsor

Oregon Health and Science University

Other

Collaborators

  • Comagine Health
  • Oregon Health Authority

Registry information

Important dates

Study start
2023
Primary completion
2026
Study completion
2026
First posted
Jan 26, 2023
Registry last updated
Jan 14, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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