PEEP Test and Gas Exchange in ALI/ARDS Patients

The investigators aim to study the effect of different levels of PEEP in ALI/ARDS patients on gas exchange.

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Key information

Conditions

Acute Respiratory Distress Syndrome Lung Diseases Respiration Disorders Respiratory Distress Syndrome Respiratory Insufficiency Respiratory Tract Diseases

Age range

16 year–90 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Policlinico Hospital

Milan, 20122, Italy

About this study

In a population of ALI/ARDS patients during mechanical ventilation we will evaluate the effect of different levels of PEEP on gas exchange and dead space.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

ALI/ARDS patients requiring mechanical ventilation

Exclusion criteria

Hemodynamic instability
Barotrauma

Treatment and study plan

mechanical ventilation

Procedure

measurement of gas exchange, dead space, respiratory mechanics 5, 15, 30, 60 minutes from PEEP change (5 and 15 cmH2O)

Primary outcomes

Gas exchange, dead space, respiratory mechanics

Time frame: 5, 15, 30, 60 minutes from PEEP change

Sponsors and collaborators

Lead sponsor

Policlinico Hospital

Other

Registry information

Official study title

Positive End Expiratory Pressure (PEEP) Test and Gas Exchange in ALI/ARDS Patients

Important dates

Study start: 2006
Primary completion: 2008
Study completion: 2008
First posted: Jan 31, 2006
Registry last updated: Sep 25, 2008

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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Completed