PEEP During Induction of Anesthesia in Small Children

Positive end-expiratory pressure (PEEP) applied during induction of anesthesia prevents atelectasis formation and increases the duration of nonhypoxic apnea in obese and nonobese patients. PEEP also prevents atelectasis formation in pediatric patients. Because pediatric patients arterial desaturation during induction of anesthesia develops rapidly, we studied the clinical benefit of PEEP applied during anesthesia induction.

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Key information

Conditions

Pediatric Anesthesia

Age range

1 month–2 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Hee-Soo Kim, Seoul, Soul-t'ukpyolsi, South Korea

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

pediatric patients undergoing general anesthesia using endotracheal intubation

Exclusion criteria

previous history of lung disease
anticipated difficulty in airway management

Treatment and study plan

PEEP

Other

7cmH2O positive end expiratory pressure

ZEEP

Other

0 cmH2O positive end expiratory pressure

Primary outcomes

Duration of Apnea

Time frame: from the start of apnea until SpO2 reached 95%, maximum 5 minutes.

Sponsors and collaborators

Lead sponsor

Seoul National University Hospital

Other

Registry information

Official study title

The Effect of Positive End-expiratory Pressure During Induction of General Anesthesia on Atelectasis Formation and Non-hypoxic Apnea Time in Small Children: a Randomized Controlled Trials

Important dates

Study start: 2018
Primary completion: 2019
Study completion: 2019
First posted: May 30, 2018
Registry last updated: Aug 19, 2019

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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Completed