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NCT Number: NCT07543549

Pediatric Renal Emergencies: Presentations and Outcomes at Sohag University Hospitals

Renal diseases in children present with a wide spectrum of clinical manifestations, ranging from mild urinary abnormalities to severe acute kidney injury requiring urgent management. Early recognition in the emergency setting is essential to improve outcomes, yet data on pediatric renal emergencies in Upper Egypt remain limited.

This prospective cohort study aims to characterize the clinical presentations of renal diseases among children presenting to the emergency room at Sohag University Hospitals, determine the prevalence of specific renal conditions, and evaluate immediate management outcomes and short-term follow-up after discharge.

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Key information

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Children aged 1 month to 18 years. Presentation to the emergency room at Sohag University Hospitals with signs and/or symptoms suggestive of renal involvement (e.g., edema, hematuria, oliguria/anuria, flank pain, hypertension).

Patients with a known history of renal disease presenting with acute exacerbation.

Written informed consent obtained from parents or legal guardians.

Exclusion criteria

  • Incomplete or missing essential clinical, laboratory, or imaging data. Refusal or inability to obtain written informed consent from parents or legal guardians.

Patients with suspected renal symptoms later confirmed to have non-renal causes.

Patients who received renal replacement therapy prior to presentation at another facility.

Treatment and study plan

Standard emergency room management

Other

Participants receive routine clinical assessment, investigations, and management according to Sohag University Hospitals emergency protocols. No study-specific intervention is applied.

Primary outcomes

  1. Frequency of Clinical Presentations and Final Diagnoses of Pediatric Renal Diseases

    Time frame: At baseline (emergency room presentation) through hospital stay (up to discharge, typically within 7 days)

    Percentage (%) of patients presenting with specific clinical features (e.g., edema, hematuria, oliguria, hypertension) assessed by clinical examination and initial laboratory investigations.

    Distribution (%) of final diagnoses (e.g., acute kidney injury, urinary tract infection, congenital anomalies, glomerular diseases) based on clinical evaluation, laboratory results, and imaging studies.

Study contacts

Contact information is provided by the study sponsor or research team.

Fady Medhat

CONTACT

[email protected]

00201284408988

Sponsors and collaborators

Lead sponsor

Sohag University

Other

Registry information

Official study title

Variable Manifestations and Outcomes of Renal Diseases Among Children Presenting to the Emergency Room at Sohag University Hospitals

Important dates

Study start
2026
Primary completion
2027
Study completion
2027
First posted
Apr 22, 2026
Registry last updated
Apr 22, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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