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Completed

NCT Number: NCT04988776

PECS II Versus ICBN Block Plus SCNB for AV Fistula Creation in CRF Patients

Brachial plexus block (BPB) is often utilized for proximal arm arteriovenous access creation. However, the medial upper arm and axilla are often inadequately anesthetized, as the Intercostobrachial nerve (which provides sensory supply to the axilla, upper medial arm, and a small area at the upper lateral chest) is not a component of the brachial plexus. This requires repeated, an intraoperative local anesthetic (LA) supplementation up to conversion into GA. The intercostobrachial nerve (ICBN) is a purely sensory nerve that arises primarily from the second intercostal nerve (T2) with occasional contribution from T3. Therefore, It is not a component of the brachial plexus and is not anesthetized by brachial plexus blockade. The ICBN can be blocked together with other nerves, such as the pectoral, intercostal, and long thoracic nerves in a recently described technique named pectoral nerves block type II (PECS II ).In this thesis, investigators compared the use of the PECS II block and ICBN block as a supplement to supraclavicular brachial plexus block for providing complete anesthesia of the upper arm for fistula creation surgery.

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Key information

Age range

18 year–70 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 1 / Phase 2

Primary location

Ashraf Magdy Eskandr

Shibīn al Kawm, Menoufia, 32951, Egypt

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • ESRD patients.
  • Proximal Arm Arteriovenous Access Surgery.
  • Elective or emergency surgery
  • American Society of Anesthesiology (ASA) physical status II to III.

Exclusion criteria

  • Inability of the patient to provide informed consent, communicate or cooperate
  • History of allergy to local anesthetics.
  • Preexisting upper limb neurological disease at the side of the surgery.
  • Patients on anticoagulant therapy or with history of coagulopathy.
  • Previous surgery at or near the site of the study.
  • The presence of skin infection at the puncture site.

Treatment and study plan

ultrasUltrasound-guided Intercostobrachial nerve block supplemental to supraclavicular block with 30 ml 0.25% bupivacaine (15 ml 0.5% bupivacaine will be added to 15 m

Other

patients recieved ultrasound-guided Intercostobrachial nerve block with 10 ml 0.25% bupivacaine (5 ml 0.5% bupivacaine will be added to 5ml 0.9% normal saline ) supplemental to supraclavicular block with 30 ml 0.25% bupivacaine (15 ml 0.5% bupivacaine will be added to 15 ml of 0.9 %Nacl ) .

ultrasound-guided pectoral nerves block type II supplemental to supraclavicular block

Other

Patients received ultrasound-guided pectoral nerves block type II with 10 ml 0.25% bupivacaine (5 ml 0.5% bupivacaine will be added to 5ml 0.9% normal saline ) supplemental to supraclavicular block with 30 ml 0.25% bupivacaine (15 ml 0.5% bupivacaine will be added to 15 ml of 0.9 %Nacl )

Primary outcomes

  1. intraoperative local anesthetic requirement

    Time frame: 1-2 hours after surgery start

    volume of local anesthetic

Secondary outcomes

  1. postoperative pain

    Time frame: 24 hours after end of surgery

    Visual analogue score (0-10) where 0=no pain and 10=the worst pain

Sponsors and collaborators

Lead sponsor

Menoufia University

Other

Collaborators

  • Mamdoh Elsayed Lotfy
  • amany aly sultan
  • reem gaber abdel-mageed

Registry information

Official study title

Comparison Between Ultrasound-guided Pectoral Nerves Block Type II and Intercostobrachial Nerve Block as a Supplement to Supraclavicular Block for Anesthesia of Proximal Arteriovenous Access in End-stage Renal Disease Patients

Important dates

Study start
2020
Primary completion
2021
Study completion
2021
First posted
Aug 3, 2021
Registry last updated
Sep 20, 2021

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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