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Completed

NCT Number: NCT01670448

PECBLOCK for the Treatment of Pain After Breast Surgery

Pain after breast cancer surgery could be severe and about 1/3 of patients will develop chronic pain. The PECBLOCK is the injection of local anesthetics between the two pectoral muscles to block pectoral nerves and intercostal nerves innervating the breast. The aim of this study is to evaluate the efficacy of the PECBLOCK performed under echoguidance in minor and major breast surgery. The prevention of chronic pain following surgery will also be evaluated.

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Key information

Conditions

Cancer Neoplasms Neurologic Manifestations Pain Pain, Postoperative Pathologic Processes Pathological Conditions, Signs and Symptoms Postoperative Complications Signs and Symptoms

Age range

18 year–85 year

Sex eligibility

Female

Study type

Interventional

Phase

Not applicable

Primary location

CHUM, Montreal, Quebec, Canada

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Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • women aged 18-85 yrs old
  • patients ASA status I-IV

Exclusion criteria

  • refusal of the PECBLOCK
  • allergy to a drug used in the protocol (local anesthetic)
  • patients with chronic pain before the surgery

Treatment and study plan

PECBLOCK under echoguidance

Procedure

Performance of block under echography

Primary outcomes

  1. Pain score at rest in the recovery room

    Time frame: 30 min after entering the recovery room or just before morphine administration if needed

    Using a 0-10 verbal numerical scale where 0 is no pain and 10 the worst pain imaginable

Secondary outcomes

  1. Total morphine consumption in the recovery room

    Time frame: in the recovery room before discharge (after 1 h on average))

    When surgery is over and the patient is brought to the recovery room, the total morphine consumption in mg used in the recovery (for pain less than 4/10) is recorded

Other outcomes

  1. Total sufentanil consumption during surgery

    Time frame: at the end of surgery (1-2 h on average)

    When surgery is over, 1-2 h on average depending if it is a tumorectomy or a mastectomy, the total sufentanil consumption in micrograms during surgery is recorded.

  2. Assess any complication from PECBLOCK

    Time frame: first 24 hours post surgery

    Cardiovascular collapse, anaphylactic shock, hematoma, bleeding..?

Sponsors and collaborators

Lead sponsor

Centre hospitalier de l'Université de Montréal (CHUM)

Other

Collaborators

  • University Hospital, Limoges

Registry information

Official study title

The Pectoral Nerve Block (PECBLOCK) for the Treatment of Pain After Breast Cancer Surgery.

Acronym: PECBLOC

Important dates

Study start
2014
Primary completion
2015
Study completion
2015
First posted
Aug 22, 2012
Registry last updated
Oct 3, 2019

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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