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Completed

NCT Number: NCT01388556

PD4PD:Partnered Dance for Parkinson Disease

Exercise is often noted as an important component in a comprehensive approach to the management of Parkinson disease (PD). Most studies of exercise have examined the effects of short-term interventions and have tested participants on their anti-Parkinson medications. As such, these studies have not been able to determine whether or not exercise may have a disease-modifying effect in people with PD. The investigators recent work has shown the potential benefits of dance as a form of exercise for individuals with PD, but, like previous work, has only examined short-term interventions. The investigators think that dance may be ideally suited for study over a longer period of time because dance incorporates many of the features recommended for inclusion in PD-specific exercise programs in a format that is known to be engaging and to enhance motivation to participate in healthful behaviors. As such, the investigators aim to determine both the short- and long-term effectiveness of a community-based dance program for individuals with Parkinson disease and to determine how physical function changes over time in individuals with PD who do not exercise as compared to those who exercise regularly. The investigators hypothesize that:

A) participation in dance will result in improved physical function, cognitive function, mood and quality of life in people with PD within 3 months,

B) additional improvements will be noted at 6 months as compared to 3 months,

C) improvements will be maintained at one year with continued, regular participation in a dance class,

D) those who do not exercise will show significant functional decline over a period of one year, a decline that will not be present in those who dance regularly.

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Key information

Age range

30 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 2 / Phase 3

Primary location

Washington University School of Medicine

St Louis, Missouri, 63108, United States

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • normal central and peripheral neurological function
  • at least grade 4/5 strength and normal joint ranges of motion in both legs, - vision corrected to 20/40 or better
  • able to walk independently for 10 feet with or without an assistive device, - normal somatosensory function in the feet (2-point discrimination, vibration, joint kinesthesia, and light touch)
  • no history of vestibular disease

Exclusion criteria

  • serious medical problem
  • evidence of abnormality other than PD-related changes on brain imaging (previously done for clinical evaluations-not part of this research)
  • history or evidence of neurological deficit other than PD that could interfere, such as previous stroke or muscle disease
  • history or evidence of orthopedic, muscular, or psychological problem

Treatment and study plan

Tango dancing

Behavioral

Twice weekly tango dance classes

Primary outcomes

  1. Motor Symptom Severity

    Time frame: 12 months

    We will use the Unified Parkinson Disease Rating Scale, Motor Subscale 3, to assess the severity of movement-related symptoms. This is a standanrdized and well-established tool composed of multiple items each scored on a 0-4 scale, with 0 indicating no impairment and 4 indication severe impairment. The overall severity of motor symptoms is determined by summing scores for all of the individual items.

Sponsors and collaborators

Lead sponsor

Washington University School of Medicine

Other

Collaborators

  • Parkinson's Disease Foundation

Registry information

Acronym: PD4PD

Important dates

Study start
2009
Primary completion
2011
Study completion
2011
First posted
Jul 6, 2011
Registry last updated
Dec 9, 2015

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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