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OpenTrials
Completed

NCT Number: NCT03977818

Patterns of Care and Outcomes in METAstatic Soft Tissue SARComa

Well-designed observational studies of individuals with rare tumors are needed to improve patient care, clinical investigations, and the education of healthcare professionals.

The patterns of care, outcomes, and prognostic factors of a cohort of 2225 patients with metastatic soft tissue sarcomas who were diagnosed between 1990 and 2013 and documented in the prospectively maintained database of the French Sarcoma Group will be analyzed with a focus on : number/frequency of systemic treatments per patient, number/frequency of patients with locoregional treatment of the metastasis, number/frequency of patients with chemotherapy, number/frequency of patients with an off-label drug.

Outcome (time-to-next treatment [TNT] and overall survival [OS]) will be reported according to histological subtype, as well as the association between TNT and OS.

Prognostic factors of OS will be investigated.

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Key information

Conditions

Sarcoma Chemotherapy Metastases Neoplasm Metastasis Neoplasms Neoplasms by Histologic Type Neoplasms, Connective and Soft Tissue Neoplastic Processes Pathologic Processes Pathological Conditions, Signs and Symptoms

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Institut Bergonié, Comprehensive Cancer Center, Bordeaux, France

Loading trial locations.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • advanced soft tissue sarcoma
  • age > 18

Exclusion criteria

-

Treatment and study plan

Primary outcomes

  1. Correlation Between Time to Next Treatment (TNT) and Overall Survival (OS) Under First-line Treatment

    Time frame: 2 years

    TNT: time from the systemic treatment onset to the next treatment or death due to any cause, whichever came first.

    OS: time from the systemic treatment onset to death

Sponsors and collaborators

Lead sponsor

Institut Bergonié

Other

Collaborators

  • French Sarcoma Group

Registry information

Official study title

Patterns of Care and Outcomes of Patients With METAstatic Soft Tissue SARComa in a Real-life Setting: the METASARC Observational Study

Acronym: METASARC

Important dates

Study start
1990
Primary completion
2017
Study completion
2017
First posted
Jun 6, 2019
Registry last updated
Sep 5, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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