Skip to main content
OpenTrials
Completed

NCT Number: NCT04689906

Patient Time and In-hospital Delay of Surgery Association With Complicated Appendicitis

This is a retrospective observational study with its main aim of evaluating possible factors associated with complicated appendicitis. Current literature supports time from symptom onset until registration as the main and maybe only determinant of the outcome if patients are operated on within 24 hours. We wish to evaluate whether this is true in all patients, or there are subgroups in which time from registration to operation is associated with complicated appendicitis.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Acute Appendicitis Appendicitis Cecal Diseases Digestive System Diseases Gastroenteritis Gastrointestinal Diseases Infections Intestinal Diseases Intraabdominal Infections

Sex eligibility

All sexes

Study type

Observational

About this study

The data to be analyzed is that of patients operated on acutely for suspected appendicitis within 10 years in one medical center. Patients undergoing interval or incidental appendectomies will not be included. The endpoint to be evaluated is complicated appendicitis (gangrenous, abscess, perforated). The independent variables will include mainly sex, age, patient time (time from symptom onset to registration), hospital time (time from registration to operation), and missed diagnosis.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • male and female patients of all ages who underwent appendectomy of acute appendicitis in a single medical center between December 1, 2006, and December 31, 2016

Exclusion criteria

  • interval appendectomy,
  • incidental appendectomy,
  • appendectomy after failed antibiotic treatment for either acute appendicitis or peri-appendicular abscess
  • patients with a non-inflamed appendix
  • those in whom symptom onset before hospitalization was not noted.

Treatment and study plan

SURGERY

Other

This is a retrospective study that includes patients operated for suspicion of acute appendicitis

Primary outcomes

  1. proportion of complicated appendicitis

    Time frame: finding during surgery/pathology

    complicated appendicitis defined as either gangrenous appendicitis, perforation with abscess, perforation with local peritonitis, perforation with diffuse peritonitis

Sponsors and collaborators

Lead sponsor

Rambam Health Care Campus

Other

Collaborators

  • Hillel Yaffe Medical Center

Registry information

Official study title

In-hospital Delay of Surgery Increases the Rate of Complicated Appendicitis in Patients Presenting With Short Duration of Symptoms: a Retrospective Cohort Study

Important dates

Study start
2006
Primary completion
2016
Study completion
2017
First posted
Dec 30, 2020
Registry last updated
Jan 5, 2021

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.