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OpenTrials
Recruiting

NCT Number: NCT07192146

Patient Reported Outcomes and Associated Factors Following Endodontic Emergency Treatment

This study aims to analyze the improvement of postoperative pain and Oral Health-Related Quality of Life (OHRQoL) following endodontic emergency treatment, as well as the contributing factors affecting the change including age, gender, tooth type, dental arch, pulpal status, percussion pain, radiographic evidence of periapical lesions, type of emergency treatment (pulpotomy / partial pulpectomy / complete pulpectomy), and occlusal adjustment.

Recruiting

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Key information

Conditions

Moderate to Severe Endodontic Pain

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age 18 years or older
  • Presence of moderate to severe pain as measured by a Numerical Rating Scale (NRS) score ≥ 4
  • Pain of endodontic origin confirmed through clinical and/or radiographic examination

Exclusion criteria

  • Refused or were unable to provide informed consent or complete the questionnaire
  • Were currently or recently taking immunosuppressive agents, long-term anti-inflammatory medications, or antibiotics
  • Had non-endodontic or mixed-origin pain
  • Had already initiated endodontic treatment on the affected tooth

Treatment and study plan

Primary outcomes

  1. Postoperative pain

    Time frame: From enrollment to the end of treatment at 2 years

    Higher scores mean a worse outcome.

Secondary outcomes

  1. Oral health-related quality of life

    Time frame: From enrollment to the end of treatment at 2 years

    Higher scores mean a worse outcome.

Other outcomes

  1. Prognostic factors associated with the improvement of postoperative pain

    Time frame: From enrollment to the end of treatment at 2 years

  2. Prognostic factors associated with the improvement of oral health-related quality of life

    Time frame: From enrollment to the end of treatment at 2 years

Study contacts

Contact information is provided by the study sponsor or research team.

Chanakarn Sinsareekul

CONTACT

[email protected]

66832759760

Pantira Thep-akrapong

CONTACT

[email protected]

66813730370

Sponsors and collaborators

Lead sponsor

Chulalongkorn University

Other

Registry information

Official study title

Patient Reported Outcomes and Associated Factors Following Endodontic Emergency Treatment: A Prospective Cohort Study

Important dates

Study start
2023
Primary completion
2025
Study completion
2025
First posted
Sep 25, 2025
Registry last updated
Sep 25, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.