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OpenTrials
Completed

NCT Number: NCT02949635

Patient Outcomes After Hospitalization in Acute Geriatric Unit

Three events can be considered of major importance for patients after a hospitalization in an AGU: death, hospital readmission, and institutionalization. Current published data do not allow the clinician to simultaneously estimate the risk of hospital readmission, institutionalization and death of an older patient according to his/her characteristics and various complications that occurred during the hospitalization. However, clinicians often need to estimate these risks at hospital discharge to adapt their therapeutic choices, their proposals post-hospital care, and provide reliable and fair information to the patient and his relatives.

Estimating simultaneously the hazard for each of these three events can be complex. Indeed, a death event hinder the observation of re-hospitalization or institutionalization if death occurs before these events. The death should be considered a competing risk in these analyzes. Hospital readmission may modify the risk of death or institutionalization and should be considered as an intermediate factor for these event. This complexity cannot be accounted with classical statistical models, like logistic regression models.

The purpose of this study is to use more appropriate statistical models (multi-state models) to better estimate simultaneously the risks of hospital readmission, institutionalization, and death of a patient given after hospitalization in AGU, and to show that accuracy of these estimations can be improved by taking into account complications that occurred during the stay in AGU.

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Key information

Conditions

Age range

75 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

CHU d'Amiens, Amiens, France

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Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age 75 years and over
  • Hospitalized in Acute Geriatric Unit
  • Covered by a health insurance

Exclusion criteria

  • Refusal to participate to the study, as expressed by the patient or his/her next of kin

Treatment and study plan

Primary outcomes

  1. Number of death after discharge

    Time frame: 3 months

Secondary outcomes

  1. Number of death after discharge

    Time frame: 12 months

  2. Number of rehospitalization after discharge

    Time frame: at 3 and 12 months

  3. Number of institutionalization (NH admissions)

    Time frame: at 12 months

  4. Number of nosocomial infectious diseases during the index hospitalization

    Time frame: 60 days

  5. Duration of clostridium difficile infection

    Time frame: 60 days

  6. Length of stay of the index hospitalization

    Time frame: 60 days

    The exact duration for this outcome will correspond to the duration of the index hospitalization

Sponsors and collaborators

Lead sponsor

University Hospital, Lille

Other

Collaborators

  • Ministry of Health, France

Registry information

Official study title

Risks of Death, Hospital Readmission, and Institutionalization After Hospitalization in Acute Geriatric Unit

Acronym: DAMAGE

Important dates

Study start
2016
Primary completion
2018
Study completion
2018
First posted
Oct 31, 2016
Registry last updated
May 14, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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