Patient-Derived Organoids for Rectal Cancer

The purpose of this study is to determine the feasibility of establishing patient-derived organoids from pre-treatment rectal adenocarcinoma biopsies.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Rectum Cancer Colorectal Neoplasms Digestive System Diseases Digestive System Neoplasms Gastrointestinal Diseases Gastrointestinal Neoplasms Intestinal Diseases Intestinal Neoplasms Neoplasms Neoplasms by Site Rectal Diseases Rectal Neoplasms

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Duke Cancer Center

Durham, North Carolina, 27710, United States

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion

Age ≥18 years old.
Able to provide informed consent.
Undergoing proctoscopy.

Exclusion

Patient not planned to receive neoadjuvant radiotherapy

Treatment and study plan

Biopsy

Other

Tissue biopsy

Primary outcomes

Number of Participants With Biopsies That Form Spherical Organoids

Time frame: Baseline

Sponsors and collaborators

Lead sponsor

Duke University

Other

Registry information

Official study title

Feasibility of Establishing Patient-Derived Organoids for Rectal Cancer: A Biospecimen Collection Protocol

Important dates

Study start: 2020
Primary completion: 2022
Study completion: 2022
First posted: May 1, 2020
Registry last updated: Aug 28, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed