PaTH Clinical Data Research Network (CDRN) Atrial Fibrillation (AF) Clinician-Patient Partnership Cohort

The primary objective is to create the PaTH Network AF Clinician-Patient Partnership Cohort, which will allow the conduct of patient-centered observational studies on AF across the multiple institutions of the PaTH network. Creating the AF Clinician-Patient Partnership Cohort will involve:

• Recruiting patients with AF to participate in the PaTH Network AF Clinician-Patient Partnership Cohort
• Administering surveys to the AF Clinician-Patient Partnership Cohort approximately every 6 months to collect patient reported outcomes (PROs)
• Collecting individual patient health record data into the AF Clinician-Patient Partnership Cohort database
• Tracking whether the patient participant has biospecimens in a PaTH site biorepository and prepare for possible sharing of biospecimens in future studies.
• Identifying potential participants for future research studies.

The secondary objectives are to use the PaTH Network AF Clinician-Patient Partnership Cohort to answer patient-centered research questions including:

• What is the incidence of complications requiring re-hospitalization after an ablation procedure for AF?
• What are the predictors of major bleeding and stroke among patients that receive each anticoagulant class (vit K antagonist, direct factor X inhibitor, direct thrombin inhibitor)?
• Is the longitudinal change in applied cognition-executive function score in AF patients associated with the choice of rate versus rhythm control and anticoagulation strategy?

Inclusion criteria

• Age: 18 years or older at time of query
• Visits: 3 non-ED outpatient visits between 1/1/2011 and 12/31/2014
• AF : AF diagnosis documented between 1/1/2011 and 12/31/2014
• AF diagnosis can be coded EHR (on billing or problem lists) and/or derived from EKG reports
• AF diagnoses associated with surgery, certain thyroid conditions, or certain medications cannot count as the qualifying AF diagnosis for inclusion in this cohort.

Exclusion criteria

• Deceased
• Not proficient in English
• Already enrolled in the PaTH Clinical Data Research Network (CDRN) Atrial Fibrillation (AF) Clinician-Patient Partnership Cohort at another PaTH institution