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Completed

NCT Number: NCT01095432

Partial Wave Spectroscopic Detection of Colon Cancer Risk

The purpose of this study is to study samples of rectal mucosa (the moist lining of the rectum) using a new light scattering technology, called partial wave spectroscopy (PWS) in patients who will undergo a standard of care colonoscopy or a flexible sigmoidoscopy and have a history of ulcerative colitis (UC).

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Key information

Conditions

Ulcerative Colitis Colitis Colitis, Ulcerative Colon Cancer Colonic Diseases Colonic Neoplasms Colorectal Neoplasms Digestive System Diseases Digestive System Neoplasms Gastroenteritis Gastrointestinal Diseases Gastrointestinal Neoplasms Inflammatory Bowel Diseases Intestinal Diseases Intestinal Neoplasms Neoplasms Neoplasms by Site

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

University of Chicago, DCAM

Chicago, Illinois, 60637, United States

About this study

The purpose of this study is to study samples of rectal mucosa (the moist lining of the rectum) using a new light scattering technology, called partial wave spectroscopy (PWS)in patients who will undergo a colonoscopy or a flexible sigmoidoscopy and have a history of ulcerative colitis (UC). PWS has been recently developed to allow scientists to learn about any changes to the cells that may indicate a risk of developing colon cancer. We believe that the PWS test will more accurately detect the risk of colon cancer.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patient must be 18 years old or older.
  • Patient is already scheduled for a standard of care colonoscopy or flexible sigmoidoscopy.
  • Patient has not received chemotherapy.
  • History of ulcerative colitis.

Exclusion criteria

  • Patient is unable to give informed consent..
  • Patient has received chemo or radiation therapy within the past 3 months.

Treatment and study plan

PWS Testing

Procedure

Partial wave spectroscopy (PWS)has been developed to allow scientists to learn about any changes to the cells that may indicate a risk of developing colon cancer.

Primary outcomes

  1. Study samples of rectal mucosa (the moist lining of the rectum) using PWS.

    Time frame: 1 year

    Samples will be collected and then shipped to Northwestern University for analysis using PWS. This is to assess accuracy of detecting the risk for colon cancer.

Sponsors and collaborators

Lead sponsor

University of Chicago

Other

Collaborators

  • Northwestern University

Registry information

Acronym: Brushings

Important dates

Study start
2010
Primary completion
2015
Study completion
2015
First posted
Mar 30, 2010
Registry last updated
May 23, 2016

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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