Selective caries removal
ProcedureThe caries is not completely removed but covered with a remineralizing material. Its purpose is to maintain pulp vitality.
Not Yet Recruiting
NCT Number: NCT07120009
Partial Pulpotomy vs Selective Removing in Deep Caries
The aim of this study was to compare the one-year results of selective caries removal and partial pulpotomy treatments in terms of pulp survival and the need for further endodontic treatment in deep carious lesions.Individuals aged 18-65 years with medically healthy mature permanent teeth with deep caries will be included. The included teeth will be randomly assigned to the selective caries removal or partial pulpotomy group. Follow-up evaluations will be performed at 6 months and 12 months. The main outcome is pulp survival as determined by clinical and radiographic success.
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Trial opening soon.
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Conditions
Age range
18 year–65 year
Sex eligibility
All sexes
Study type
Interventional
Phase
Not applicable
Who can participate
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
- Individuals aged 18-65
- ASA I or II general health status
- Deep primary or secondary caries lesion (up to 75% dentin thickness)
- Restorable permanent teeth with mature apex
- Teeth without clinical and radiographic periapical pathology
Exclusion criteria
- Pregnancy
- Periapical lesion
- Spontaneous pain or tenderness to palpation
- Teeth for which pulp opening or crown/root supported prosthesis is planned
- Localized severe periodontitis
Treatment and study plan
partial pulpotpmy
ProcedureComplete cleaning of the caries resulting in pulp expose. pulp tissue is surgically removed by 1-3 mm.The aim is to remove the inflamed superficial pulp tissue to allow healing from the underlying healthy tissue.
Primary outcomes
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Assessment of pain
Time frame: 6th and 12th month
Detailed medical history
- Is the pain constant or intermittent?
- How severe is the pain? The outcome will be evaluated using the Visual Analog Scale (VAS), which ranges from 0 to 10, with higher scores indicating a worse outcome.
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Periapical pathology
Time frame: 6th and 12th month
Standardized digital periapical radiographs will be taken using the long cone paralleling technique to assess periapical status, presence of radiolucent lesions, and periodontal ligament space. Radiographs will be obtained at baseline, 6 months, and 12 months to monitor treatment outcomes and detect any pathological changes.
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Tenderness to percussion
Time frame: 12th month
- Usually, the back of a dental mirror handle or the handle of a periodontal probe is used.
- First, vertical percussion (lightly tapping the occlusal surface from above) is performed, followed by lateral percussion (lightly tapping the side of the tooth) if necessary.
- It is compared with other teeth in the same area. If the pain is only in one tooth, it suggests pathology.
- The patient describes the pain as "aching," "discomfort," or "severe pain." This severity indicates the severity of the inflamation
Study contacts
Contact information is provided by the study sponsor or research team.
Sponsors and collaborators
Lead sponsor
Cukurova University
Other
Registry information
Official study title
Selective Caries Removal Versus Partial Pulpotomy in the Treatment of Deep Caries: A Randomized Controlled Trial
Important dates
- Study start
- 2025
- Primary completion
- 2026
- Study completion
- 2026
- First posted
- Aug 13, 2025
- Registry last updated
- Aug 13, 2025
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.