Skip to main content
OpenTrials
Recruiting

NCT Number: NCT05198661

Paraneoplastic Neurological Syndromes and Autoimmune Encephalitis Collection

Numerous neurological disorders affecting the central and peripheral nervous system can be attributed to the immune system through multiple effector mechanisms. However, current treatments could be drastically improved by faster and more accurate diagnosis. The sample collection will benefit to patients with rare neuroimmune syndromes such as Autoimmune Encephalitis (AE) and Paraneoplastic Neurological Syndromes (PNS) leading to a better and early diagnosis, as well as treatment improvement.

Recruiting

Interested in participating?

Request Info

Key information

Conditions

Paraneoplastic Neurological Syndromes or Autoimmune Encephalitis Autoimmune Diseases Autoimmune Diseases of the Nervous System Immune System Diseases Nervous System Diseases

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Neurology, Pointe à Pitre, Guadeloupe, France

Loading trial locations.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patient with consent
  • Patient with well-characterized antibodies in serum or cerebrospinal fluid or not
  • Patient with neurological disorder compatible with PNS or auto-immune encephalitis

Exclusion criteria

  • Refusal of consent
  • Patient under guardianship

Treatment and study plan

Collection of biological sample with sera, CSF, buffy coat, PBMC, plasma.

Biological

Blood is collected only one time by blood sample to obtain serum, buffy coat, plasma and PBMC.

2 *4ml of blood on dry tube 2 *4ml of blood on EDTA tube If possibility of delivery in 48 hours at the Centre of Biological Resources, 7*4ml of blood on heparin tube If cerebrospinal fluid has been drawn for diagnosis, remaining sample available will be stored in the collection

Primary outcomes

  1. Blood Samples

    Time frame: 10 years

    Assessment of biocollection of blood samples

  2. Cerebrospinal fluid biocollection

    Time frame: 10 years

    Assessment of biocollection of Cerebrospinal fluid

Secondary outcomes

  1. Scientific collaboration

    Time frame: 10 years

    Number of project issued from the biocollection

  2. Scientific

    Time frame: 10 years

    Number of scientific papers issued from the biocollection

Study contacts

Contact information is provided by the study sponsor or research team.

Geraldine PICARD

CONTACT

[email protected]

4 72 35 58 42 ext. +33

Jerome HONNORAT, Pr

CONTACT

[email protected]

4 72 35 78 06 ext. +33

Sponsors and collaborators

Lead sponsor

Hospices Civils de Lyon

Other

Registry information

Acronym: SNP

Important dates

Study start
2022
Primary completion
2032
Study completion
2032
First posted
Jan 20, 2022
Registry last updated
Feb 29, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.