Palatability of a Novel Oral Formulation of Prednsione

Inclusion criteria

• age 18 to 32 years, male and female who are healthy at the time of study
• can demonstrate holding 10 mL of apple juice in mouth for 5 seconds without swallowing and then expectorate contents into a cup
• demonstrate ability to complete study questionnaire

Exclusion criteria

• history of smoking or using any tobacco products
• previous history of taste disturbance
• any condition or dietary habit known to interfere with the sense of smell and taste
• any structural or functional abnormality of the upper gastrointestinal tract
• ingestion of any medication or nutritional supplement (with exception of acetaminophen tablets or capsules) in a 48 hour period prior to study
• history of any significant illness within the two weeks prior to study
• history of autonomic dysfunction, bronchospastic disease or atopic allergy
• known hypersensitivity (ie., allergic reaction) to any drug, food coloring agent or artificial sweetener
• any history of participating in a clinical trial of a drug or device within a 30 day period from the time of study
• brushing of the teeth, usage of mouthwash, and or oral ingestion of any substance within two hours of receipt of the initial test article and
• inability to speak and/or read English at a grade 10 level