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Completed

NCT Number: NCT07041632

Pain Relief in Women Undergoing Oocyte Retrieval (OR) With Electro-acupuncture (EA) or Conscious Sedation (CS) in a Single Assisted Reproduction Centre.

This study aims to determine whether one can replace pain relief in women undergoing oocyte retrieval (OR) using electro-acupuncture (EA) instead of conscious sedation (CS).

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Key information

Conditions

Pain Intensity Assessment

Age range

21 year–45 year

Sex eligibility

Female

Study type

Interventional

Phase

Not applicable

Primary location

Centre for Assisted Reproduction

Singapore, 165608

About this study

A total of 60 women were randomized and 29 women were on electro-acupuncture (EA) versus 27 women on conscious sedation (CS) with intravenous medication for transvaginal egg extraction (OR) in IVF. Pain scores were recorded before , during and after egg extraction when the women were on conscious sedation and electro-acupuncture. Side effects were recorded. Physical parameters were recorded. Livebirth outcome were also recorded.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

all women undergoing ivf and have given consent -

Exclusion criteria

women who have infectious skin diseases, women who were unwilling to accept acupunture, history of bleeding disorders.

-

Treatment and study plan

electro-acupuncture

Other

electro-acupuncture for pain relief in egg collection in IVF

Conscious sedation

Other

IVf egg collection using conscious sedation as the usual analgesia

Primary outcomes

  1. Pain relief during egg collection

    Time frame: from start of egg collection. to 120 minutes after egg collection

    Pain score 1 to 10 during egg collection in IVF compared between using acupuncture and conscious sedation

Secondary outcomes

  1. Stress, satisfaction measurement and physical parameters between acupuncture and conscious sedation during egg collection in IVF

    Time frame: Up to 120 minutes after egg collection

    Stress score and satisfaction outcome scores 0 to 10 for pain relief between acupuncture and conscious sedation during egg collection were recorded. For the stress score, zero is equivalent to no stress and 10 indicates the worst possible stress. For the satisfaction score, zero is equivalent to no satisfaction at all and 10 is the highest satisfaction.

Sponsors and collaborators

Lead sponsor

Singapore General Hospital

Other

Collaborators

  • Ministry of Health, Singapore

Registry information

Official study title

Can Acupuncture Replace Conscious Sedation in In-Vitro-Fertilization Transvginal Oocyte Retrievals?

Acronym: EA

Important dates

Study start
2015
Primary completion
2017
Study completion
2018
First posted
Jun 27, 2025
Registry last updated
Jun 27, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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