Skip to main content
OpenTrials
Recruiting

NCT Number: NCT07409688

Pain Relief Following Laparoscopic Cholecystectomy While Comparing Intra Abdominal Versus Sub Cutaneous Local Anesthetic Administration

Laparoscopic cholecystectomy involves removal of gallbladder through small incision ports resulting in faster recovery. Small incisions are less painful and hence local anesthesis administered can be effective for pain management. This local anesthetic can be administered either within abdominal cavity or at sit of small incisions.

Recruiting

Interested in participating?

Request Info

Key information

Conditions

Laparoscopic Cholecystectomy Surgery Analgeisa Local Anesthetic Infiltration

Age range

15 year–60 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 4

Primary location

Rawalpindi Teaching Hospital, Rawalpindi

Rawalpindi, Punjab Province, Pakistan

Location status: Recruiting

About this study

Laparoscopic cholecystectomy is a minimally invasive surgical procedure involving removal of the gallbladder through multiple small trocar incisions. Compared with open surgery, this approach is associated with reduced postoperative pain, shorter hospital stay, and faster recovery. Despite its minimally invasive nature, postoperative pain remains a significant concern, particularly at port sites and from intraperitoneal irritation. Local anesthetic techniques have been shown to contribute to multimodal analgesia in laparoscopic surgery. Local anesthetic agents may be administered either intraperitoneally or by infiltration at trocar insertion sites to reduce postoperative pain and opioid requirements. However, the optimal route of local anesthetic administration for effective postoperative analgesia following laparoscopic cholecystectomy remains uncertain, warranting further clinical evaluation.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • ASA I and II

Exclusion criteria

  • Allergic to local anesthetic Open cholecystectomy History of chronic pain History of abdominal surgery

Treatment and study plan

Intraoperitoneal local anesthetic administration

Drug

Intraperitoneal infiltration of 20ml of 0.25% Bupivacaine will be done at the end of procedure by the surgeon.

Sub cutaneous administration of local anesthetic

Drug

port site infiltration of 20ml of 0.25% Bupivacaine will be done. 6ml for 10mm ports and 4ml for 5mm ports respectively.

Primary outcomes

  1. Post opestive pain score

    Time frame: This will be measured using Visual Analog score upon arrival at post anesthesia care unit labelled as Time 0 then at time intervals 3h,6h, 12h and 24 hours post operatively

  2. Rescue analgesia demand

    Time frame: This will be the number of patients requiring resuce analgesia in 24h post operative period. Rescue analgesia will be administered if VAS score >4

Study contacts

Contact information is provided by the study sponsor or research team.

Nimrah Iqbal Prinicpal Investigator, MBBS

CONTACT

[email protected]

+92 335 0526611

Sponsors and collaborators

Lead sponsor

Rawalpindi Medical College

Other

Registry information

Official study title

Comparative Evaluation of Analgesic Outcomes of Intra-peritoneal Versus Subcutaneous Infiltration of Bupivacaine for Laparoscopic Cholecystectomy Patients "

Important dates

Study start
2026
Primary completion
2026
Study completion
2026
First posted
Feb 13, 2026
Registry last updated
Feb 13, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.