Mayo Clinic in Rochester
Rochester, Minnesota, 55905, United States
Location status: Recruiting
NCT Number: NCT05285566
The purpose of this study is to find out whether injecting the U.S. Food and Drug Administration (FDA) approved drug EXPAREL®, a long acting (approximately 96 hours) numbing medication, will reduce pain after rib cartilage removal in comparison to the standard injection of XYLOCAINE®.
Interested in participating?
Request Info18 year and older
All sexes
Interventional
Phase 4
Rochester, Minnesota, 55905, United States
Location status: Recruiting
Healthy volunteers accepted: Yes
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
Impaired renal function as documented in the medical record in the last 3 months with a serum creatinine greater than 1.2 mg/dL or glomerular filtration rate < 60 mL/min/BSA as determined by history or review of the medical record.
106mg (8 mL) subcutaneous injection injected after costal cartilage harvest
Other names: Liposomal bupivacaine
8 mL of 1% lidocaine with 1:100,000 of epinephrine into costal cartilage wound site
Other names: Lidocaine
Time frame: 7-10 days following the last administration of study treatment
Measured using a visual analog scale 0=no pain and 10=worst possible
Time frame: 7-10 days following the last administration of study treatment
Total oral pain medication usage self-reported in pain medication diary
Time frame: 7-10 days following the last administration of study treatment
Total number of adverse reactions reported to the study agent
Contact information is provided by the study sponsor or research team.
Mayo Clinic
Other
A Phase IV Randomized, Single-Blind Trial of Liposomal Bupivacaine (Exparel®) for Pain Control in Costal Cartilage Harvest
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
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