PABLOS 2.0 - Chronic Pain After Sternotomy

PABLOS 2.0 is a non-interventional cohort study with prospective data collection by telephone questionnary, with three groups from a single-center superiority interventional study. Patients remained blinded for the duration of the study.

The patients in the cohort come from the precedent PABLOS study (NCT05345639). They receive oral and written information, and confirm orally their non-opposition to participating in the PABLOS 2.0 study.

The specific procedures of the PABLOS 2.0 study are the collection using a telephone questionnary of the score of the numerical scale (from 0 to 10) of pain at rest and with effort, of the DN4 (proportion of chronic pain with a neuropathic component), of the EQ-5D-5L scale (quality of life) and of consumption of painkillers.

Inclusion criteria

• Patient who participated in the PABLOS study (See below);
• French-speaking patient, able to understand and answer a questionnary

Exclusion criteria

• Patient who has had an operation for cardiac or thoracic surgery, including a REDUX (surgical revision) of sternotomy since their inclusion in the PABLOS study;
• Patient opposing the research.

PABLOS criteria (NCT05345639) :

Pre-inclusion criteria

• Adult patient (≥18 years old);
• Patient having planned cardiac surgery with performance of a sternotomy at the Angers University Hospital;
• Patient having signed consent;
• French-speaking patient, able to understand and answer a questionnary;
• Patient affiliated to or beneficiary of a social security scheme;

Criteria for confirming inclusion

• Hemodynamic stability at the end of surgical intervention;
• Absence of bleeding justifying immediate surgical revision

Non-inclusion criteria

• Known hypersensitivity to local anesthetics with amide bonds;
• Operation for cardiac surgical revision, including REDUX (surgical revision) of sternotomy;
• Emergency surgery;
• Surgery in a septic context (Endocarditis, Intravascular device infection);
• Weight less than 30kg;
• Severe psychiatric or cognitive disorder hindering assessment by questionnary;
• Pregnant, breastfeeding or parturient woman;
• Person deprived of liberty by judicial or administrative decision;
• Person subject to psychiatric care under duress;
• Person subject to a legal protection measure;
• Inclusion in another interventional study modifying post-operative pain management.