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Active, Not Recruiting

NCT Number: NCT05227105

PA Moves Trial - Patient Participants

The purpose of this study is to address physical inactivity in rural populations in Pennsylvania.

Active, Not Recruiting

This study is active but is not currently recruiting participants.

Key information

About this study

People living in rural areas are diagnosed and die from cancer at higher rate than people living in cities. Physical activity has been shown to decrease the risk and occurrence of a variety of cancers, including bladder, breast, colon, endometrial, gastric, kidney, and prostate cancers. Being inactive can cause over 10% of breast and colon cancer cases.

Compared to people living in cities, people living in rural areas tend to be less physically active. They're also more likely to be overweight/obese or have diabetes. Adults who are overweight, obese, or diabetic often have changes in the way their bodies deal with insulin, glucose metabolism, and inflammation. Physical activity is thought to reduce the risk of cancer by improving these issues over time.

Primary care providers and their staff can identify a patient's need for more physical activity, but may not have the time or resources to give advice or assistance. We have set up a telephone-based physical activity coaching program, called the MoveLine, to give inactive patients advice and assistance in becoming more physically active.

The purpose of this study is to determine if referring inactive patients to the MoveLine will help them to be more physically active over time. Approximately 880 people will take part in this research in rural areas of Pennsylvania.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Adults aged 18 - 75 at the time of enrollment
  • Either overweight/obese (Body Mass Index (BMI) ≥ 25) or diabetic (hemoglobin A1c ≥ 5.7%)
  • Physically inactive (defined as < 90 min/week of self-reported structured physical activity)
  • Able to speak, read, and understand the English language
  • Resides in a rural area of Pennsylvania with a Rural Urban Continuum Code (RUCC) 4 - 9 or Rural-Urban Commuting Area (RUCA) code 4 - 10
  • Must be able to provide and understand informed consent
  • Primary care patient of one of the participating providers
  • Self-report ability to walk ¼ mile
  • Access to a telephone

Exclusion criteria

  • Cardiac exclusion criteria: Class II, III, or IV heart failure as defined by the New York Heart Association (NYHA) functional classification system, history of acute coronary syndromes, uncertain or uncontrolled arrhythmia, uncontrolled hypertension, syncope, acute myocarditis, acute pericarditis, acute endocarditis, acute pulmonary embolus or pulmonary infarction, thrombosis of lower extremities, suspected dissecting aneurysm, pulmonary edema, respiratory failure, or acute non-cardiopulmonary disorder that may affect exercise performance or be aggravated by exercise
  • Mental impairment leading to inability to cooperate, provide informed consent, or follow study instructions
  • Evidence in the electronic medical record of an absolute contraindication for physical activity
  • Severe or advanced orthopedic conditions
  • Use of assistive devices for ambulation
  • Resides outside of a rural area of Pennsylvania (i.e., one that is not RUCC code 4 - 9 OR RUCA code 4 - 10)
  • Pregnant women

Treatment and study plan

Physical activity

Behavioral

Physical activity will be encouraged up to an amount of 150 minutes per week.

Delayed Intervention

Behavioral

Physical activity will be encouraged at the end of the trial.

Primary outcomes

  1. Physical Activity Questionnaire

    Time frame: 12 months vs. baseline

    The 11-question Morgenstern Physical Activity Questionnaire (PAQ-M) is a self-report of physical activity resulting from recreational activities, exercises, home or work activities, and chores.

  2. Objective accelerometry

    Time frame: 12 months vs. baseline

    An accelerometer will be worn for one week to track physical activity.

Secondary outcomes

  1. Physical Activity Questionnaire

    Time frame: 24 months vs. baseline; 24 months vs. 12 months

    The 11-question Morgenstern Physical Activity Questionnaire (PAQ-M) is a self-report of physical activity resulting from recreational activities, exercises, home or work activities, and chores.

  2. Objective accelerometry

    Time frame: 24 months vs. baseline; 24 months vs. 12 months

    An accelerometer will be worn for one week to track physical activity.

Sponsors and collaborators

Lead sponsor

University of Pittsburgh

Other

Collaborators

  • National Cancer Institute (NCI)

Registry information

Official study title

Increasing Physical Activity in Rural Pennsylvanians: The PA Moves Trial

Important dates

Study start
2023
Primary completion
2027
Study completion
2027
First posted
Feb 7, 2022
Registry last updated
Apr 21, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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