Skip to main content
OpenTrials
Completed

NCT Number: NCT03933137

P-POSSUM Score and Length of Stay

P-POSSUM score had a predictive power of >80% to predict the length of stay of kidney transplant recipients

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Rumah Sakit Cipto Mangunkusumo

Jakarta Pusat, DKI Jakarta, 10430, Indonesia

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Subjects are medical record of recipients who underwent kidney transplant

Exclusion criteria

  • Medical record was incomplete
  • Patients who died during surgery or before the patient was discharged.

Treatment and study plan

Portsmouth Physiological and Operative Severity Score for the Enumeration of Mortality and Morbidity (P-POSSUM) score

Other

P-POSSUM score's variables are divided into physiological parameters (age, cardiac, respiratory, ECG, systolic blood pressure, pulse rate, haemoglobin, leukocyte count, urea, sodium plasma, potassium plasma, and GCS) and operative parameters (operation type, number of procedures, operative blood loss, peritoneal contamination, malignancy status, CEPOD).

Primary outcomes

  1. Correlation between each variable of P-POSSUM and length of stay

    Time frame: 1 day before surgery until discharged from hospital, up to 30 days

    Correlation between 18 variables (12 variables as physical parameters and 6 variables as operative parameters) and length of stay

  2. P-POSSUM score Discrimination

    Time frame: 1 day before surgery until discharged from hospital, up to 30 days

    P-POSSUM score ability to discriminate length of stay based on variable scores: physical parameters and operative parameters

  3. P-POSSUM score Calibration

    Time frame: 1 day before surgery until discharged from hospital, up to 30 days

    P-POSSUM score cutoff to predict length of stay based on variable scores: physical parameters and operative parameters

Secondary outcomes

  1. Patient's length of stay post kidney transplantation

    Time frame: From post surgery until discharged from hospital, up to 30 days

    Patient's length of stay post kidney transplantation

  2. P-POSSUM score (physical parameters): Age

    Time frame: 1 day before surgery

    The score for Age variable cut-off:

    • point for <61 years
    • point for 61-71 years

    4 point >71 years

  3. P-POSSUM score (physical parameters): Heart disease

    Time frame: 1 day before surgery

    The score for heart disease variable cut-off:

    • point for no heart failure
    • point for diuretic, digoxin or angina/hypertension medicine usage

    4 point for peripheral edema, warfarin, or borderline cardiomegaly on chest X-ray (CXR)

  4. P-POSSUM score (physical parameters): Lung disease

    Time frame: 1 day before surgery

    The score for lung disease variable cut-off:

    • point for no dyspnea
    • points for exertional dyspnea or mild COPD on CXR

    4 points for limiting dyspnea or moderate COPD on CXR 8 points for dyspnea at rest or fibrosis/consolidation on CXR

  5. P-POSSUM score (physical parameters): ECG abnormality

    Time frame: 1 day before surgery

    The score for ECG abnormality variable cut-off:

    1 point for normal ECG 4 points for atrial fibrillation (HR 60-90 8 points for 5 ectopic beats/min, Q waves or ST/T wave change

  6. P-POSSUM score (physical parameters): Systolic blood pressure

    Time frame: 1 day before surgery

    The score for systolic blood pressure variable cut-off:

    • point for 110 - 130 mmHg
    • points for 100-109 mmHg or 131-170 mmHg

    4 points for > 170 mmHg or 90-99 mmHg 8 points for < 90 mmHg

  7. P-POSSUM score (physical parameters): Pulse rate

    Time frame: 1 day before surgery

    The score for pulse rate variable cut-off:

    • point for 50-80 beats per minute (bpm)
    • points for 40-59 bpm or 81-100 bpm

    4 points for 101-120 bpm 8 points for > 121 bpm or < 40 bpm

  8. P-POSSUM score (physical parameters): Hemoglobin

    Time frame: 1 day before surgery

    The score for hemoglobin variable cut-off:

    • point for 13-16 g/dL
    • points for 11.5-12.9 or 16.1-17 d/dL

    4 points for 10-11.4 or 17.1-18 g/dL 8 points for <10 or >18 g/dL

  9. P-POSSUM score (physical parameters): Leukocyte count

    Time frame: 1 day before surgery

    The score for leukocyte count variable cut-off:

    • point for 4.000-10.000/mm3
    • points for 10.100-20.000 atau 3.100-4.000/mm3

    4 points for >20.000 atau <3.000/mm3

  10. P-POSSUM score (physical parameters): Plasma potassium concentration

    Time frame: 1 day before surgery

    The score for plasma potassium concentration variable cut-off:

    • point for 3.5-5 mmol/L
    • points for 3.2-3.4 or 5.1-5.3 mmol/L

    4 points for 2.9-3.1 or 5.4-5.9 mmol/L 8 points for <2.9 or >5.9 mmol/L

  11. P-POSSUM score (physical parameters): Plasma sodium concentration

    Time frame: 1 day before surgery

    The score for plasma sodium concentration variable cut-off:

    • point for >135 mmol/L
    • points for 131-135 mmol/L

    4 points for 126-130 mmol/L 8 points for <126 mmol/L

  12. P-POSSUM score (operative parameters): Number of procedures

    Time frame: 1 day before surgery

    The score for number of procedures variable cut-off:

    1 point for one 4 points for two 8 points for more than two

  13. P-POSSUM score (operative parameters): Intraoperative blood loss

    Time frame: Intraoperative

    The score for intraoperative blood loss variable cut-off:

    • point for <100 mL
    • points for 101-500 mL

    4 points for 501-999 mL 8 points for > 999 mL

  14. P-POSSUM score (operative parameters): Peritoneal contamination/soiling

    Time frame: Intraoperative

    The score for peritoneal contamination/soiling variable cut-off:

    • point for none
    • points for minor (serous fluid)

    4 points for local pus 8 points for free bowel content, pus or blood

  15. P-POSSUM score (operative parameters): Presence of malignancy

    Time frame: 1 day before surgery

    The score for presence of malignancy variable cut-off:

    • point for none
    • points for primary only

    4 points for nodal metastases 8 points for distant metastases

  16. P-POSSUM score (operative parameters): Mode of surgery

    Time frame: 1 day before surgery

    The score for mode of surgery variable cut-off:

    1 point for elective 4 points for emergency resuscitation of > 2 hours possible operation < 24 hours after admission 8 points for emergency (immediate surgery < 2 hours needed)

Sponsors and collaborators

Lead sponsor

Indonesia University

Other

Registry information

Official study title

Correlation Between P-POSSUM Score and Length of Stay in Kidney Transplant Recipients

Important dates

Study start
2018
Primary completion
2018
Study completion
2018
First posted
May 1, 2019
Registry last updated
May 1, 2019

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.