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Completed

NCT Number: NCT02745431

Oxytocin Effects on Likeability After Being Liked or Disliked

The current study aimed to investigate oxytocin effect on the response after the experience of being liked or disliked.

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Key information

Conditions

Social Behavior Behavior

Age range

18 year–30 year

Sex eligibility

Male

Study type

Interventional

Phase

Not applicable

Primary location

School of Life Science and Technology, University of Electronic Science and Technology

Chengdu, Sichuan, 611731, China

About this study

In a double-blind, between-subject, placebo controlled design study, the researchers aimed to investigate the intranasal OXT (40IU) treatment on rating response after being liked or disliked in healthy male subjects. All subjects completed a range of questionnaires measuring personality and affective traits and levels of anxiety: Positive and Negative Affect Schedule (PANAS) , State-Trait Anxiety Inventory (STAI) , Beck Depression Inventory (BDI), Cheek and Buss shyness Scale (CBSS),Autism Spectrum Quotient (ASQ), Empathy Quotient(EQ) before self-administration.Study participants were led to believe that other participants had formed an opinion on their likability based on their appearance in a photograph and they passively viewed the responses (like or dislike) from 'other participants'. After that, they rated 'other participants' about likeability (how much do you like the person), accuracy (have you seen the person), feeling (how good do you feel), and tendency (how much would do like have him/her as a friend). Likeability, tendency, feeling and accuracy were included into analysis as dependent variables.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Healthy subjects without past or current psychiatric or neurological disorder

Exclusion criteria

  • history of head injury;
  • claustrophobia;
  • medical or psychiatric illness.

Treatment and study plan

Oxytocin

Drug

Placebo

Drug

Primary outcomes

  1. Oxytocin effect on likeability after being liked or disliked

    Time frame: 2 hour

    Likeability rating was included into analysis as dependent factor.

Secondary outcomes

  1. Relationship status may influence oxytocin effect

    Time frame: 2 hour

    subjects were subdivided into two subgroups

Sponsors and collaborators

Lead sponsor

University of Electronic Science and Technology of China

Other

Registry information

Important dates

Study start
2015
Primary completion
2016
Study completion
2016
First posted
Apr 20, 2016
Registry last updated
Aug 1, 2017

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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