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Completed

NCT Number: NCT03228901

Oxytocin and Non-verbal Communication

In this protocol registration, the investigators plan a secondary data analysis of a dataset to explore the effects of intra-nasal oxytocin on the non-verbal expression of affiliation.

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Key information

Conditions

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 2

Primary location

University of New South Wales

Sydney, New South Wales, 2052, Australia

About this study

Using Liu et al.'s (2012) dataset, the investigators seek to observe whether the administration of oxytocin modifies non-verbal communication with a stranger.

This dataset involves a conversation between two strangers that took place 45 minutes after drug administration. While Liu et al. coded the video for markers of interpersonal distance (physical distance, eye contact, conversational intimacy), the investigators seek to analyse oxytocin's effects on non-verbal communication of affiliative and sexual cues (e.g., smiles, lip puckers). Based on findings that oxytocin's effects depend on context, the investigators will explore these relationships as a function of the conversational context (where participants converse with each other using low-, medium-, and high-intimacy topics, or in an unstructured conversation).

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • healthy

Exclusion criteria

  • pregnant;
  • history of epilepsy, severe depression, severe anxiety, or psychosis;
  • smoking more than 15 cigarettes a day;
  • addicted to illegal substances.

Treatment and study plan

Oxytocin

Drug

Administration of the hormone oxytocin

Other names: Syntocinon

Placebos

Drug

Primary outcomes

  1. Non-verbal communication

    Time frame: Measured in the interaction which commenced 45mins after drug administration

    Based on coding the video-recorded interaction between two strangers, using a coding scheme by Gonzaga et al. (for affiliative and sexual cues)

Secondary outcomes

  1. Ratings of the person participants interacted with

    Time frame: Measured following the interaction (which commenced 45 mins after drug administration)

    Positivity or sexual attraction towards the other participant in the conversation (as measured using visual analogue scales based on person perception studies)

Sponsors and collaborators

Lead sponsor

Yale-NUS College

Other

Registry information

Official study title

Exploring the Effects of Oxytocin on Non-verbal Communication

Important dates

Study start
2007
Primary completion
2009
Study completion
2009
First posted
Jul 25, 2017
Registry last updated
Jul 27, 2017

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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