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OpenTrials
Completed

NCT Number: NCT01779076

Oxygen Level and Safe Emergence From Anesthesia

Using a protective ventilation strategy during general anesthesia from pre-oxygenation to emergence and selecting patients without risk of a difficult airway or intubation, a lower fraction of inspiratory oxygen (FIO2) can be used during extubation. This might reduce the postoperative area of atelectasis without desaturations becoming more common.

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Key information

Conditions

Focus of Study is Postoperative Pulmonary Atelectacis

Age range

30 year–85 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Västmanlands sjukhus Köping

Köping, Västmanland County, 731 81, Sweden

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • No sign of difficult airway or intubation
  • Day case surgery in total intravenous anesthesia with laryngeal mask airway without adding regional anesthesia of plexus brachialis or muscle relaxant.
  • Body mass index less than 35.
  • American Society of Anesthesiologists physical status (ASA) class I-III

Exclusion criteria

  • Body mass index 35 or higher
  • Increased risk of aspiration
  • Obstructive sleep apnea syndrome
  • Procedures during surgery making a former easy airway a difficult airway
  • Need for opioids after extubation
  • Hypothermia

Treatment and study plan

30% oxygen

Procedure

100% oxygen

Procedure

Primary outcomes

  1. Area of atelectasis

    Time frame: 30 minutes

    The area of atelectasis is investigated by computed tomography of the lungs postoperatively

Secondary outcomes

  1. Peripheral oxygen saturation (SpO2)

    Time frame: 3 hours

    SpO2 is continuously assessed postoperatively.

Sponsors and collaborators

Lead sponsor

Region Västmanland

Other

Registry information

Official study title

Emergence From General Anesthesia With Laryngeal Mask Airway and Increased End-expiratory Pressure Using 30% Oxygen is as Safe as With 100% Oxygen But Reduces the Area of Post Operative Atelectasis.

Important dates

Study start
2013
Primary completion
2013
Study completion
2013
First posted
Jan 30, 2013
Registry last updated
Jan 17, 2018

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.