Ovarian Cancer Hemoscope Trial

This is a prospective, gold standard observational trial designed to enroll consecutive, consenting ovarian cancer patients for the purpose of determining sensitivity of an assay that detects circulating tumor DNA. This observational pilot trial will also be used to examine the genetic variants/mutations present in the tumor tissue DNA.

Active, Not Recruiting

This study is active but is not currently recruiting participants.

Key information

Conditions

Ovarian Neoplasms Adnexal Diseases Endocrine Gland Neoplasms Endocrine System Diseases Female Urogenital Diseases Female Urogenital Diseases and Pregnancy Complications Genital Diseases Genital Diseases, Female Genital Neoplasms, Female Gonadal Disorders Neoplasms Neoplasms by Site Ovarian Diseases Urogenital Diseases Urogenital Neoplasms

Age range

18 year and older

Sex eligibility

Female

Study type

Observational

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Case Group

Patients with ovarian cancer undergoing surgery (all stages)
Over 18 years old

Control Group

Patients with a benign gynecological condition undergoing surgery
Over 18 years old

Exclusion criteria

Previous cancer diagnosis (all)
Radiation therapy before surgical treatment
Bone marrow transplant
Chemotherapy before surgical treatment
Invasive procedure resulting in damage to tissue (e.g., surgery, biopsy, thermal ablation) in the 7 days prior to baseline (pre-surgical) blood collection

Treatment and study plan

Primary outcomes

Sensitivity of an assay that detects circulating tumor DNA

Time frame: 3 years

Sponsors and collaborators

Lead sponsor

Scripps Translational Science Institute

Other

Registry information

Important dates

Study start: 2016
Primary completion: 2025
Study completion: 2030
First posted: Jun 23, 2016
Registry last updated: Jan 16, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Active, Not Recruiting