Outpatient Treatment of Low-Risk Venous Thromboembolism With Target Specific Anticoagulant

Information will be obtained from the patient medical records, past medical history, physical examination at initial outpatient clinic visit 30 days (+/- 14 days) and 6 months or 180 days (+/- 14 days) post diagnosis or start of treatment, then annual follow ups for up to 5 years. The data will be collected and stored in a database, the IU RedCap database system will be used to develop a database and store information .

Inclusion:

• DVT or PE diagnosed on imaging:
• Systolic always>100 mm Hg in absence of history of low blood pressure
• No contraindication to anticoagulation treatment (active bleeding or high risk postoperative status, creatinine clearance < 30 ml/min, history of heparin induced thrombocytopenia or warfarin skin necrosis);
• No other medical condition requiring hospital treatment (sepsis, new or decompensated existing organ failure, intractable pain);
• No social condition requiring hospital treatment (homelessness with history of non-adherence to treatment, suspected neglect or abuse, incarceration, untreated psychosis, severe alcohol or drug dependency);
• No coagulopathy or current anticoagulant resulting in an INR>1.7, or thrombocytopenia (platelet count < 50,000/uL);
• No need for supplemental oxygen (no respiratory distress and pulse ox always >94%)

Exclusion:

• If active cancer, POMPE-C <6%