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Enrolling by Invitation

NCT Number: NCT03037242

Outcomes of Meniscus Root Repair Using a Transtibial Pullout Technique

The results of this study will optimize the care for patients with a meniscus root tear. Surgeons will be able to determine if MRR (meniscus root repair) with transtibial pullout technique is an effective treatment and will identify potential risk factors for poor clinical outcomes. In addition, investigators will determine if MRR is successful in delaying the radiographic progression of arthritis in the involved compartment.

Enrolling by Invitation

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Key information

Conditions

Meniscus Tear

Age range

18 year–65 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Mayo Clinic, Rochester, Minnesota, United States

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About this study

The loss of attachment at the root of the meniscus impairs the ability to maintain hoop strain when the tibiofemoral joint is loaded. This loss of hoop strain is responsible for the increased pressure on the articular cartilage.

This new awareness has prompted surgeons to consider surgical repair for treatment of meniscal root avulsions. Despite this recent focus on results of surgical repair, prospective studies are lacking, and the optimal surgical indications and technique have not been optimized.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Meniscus root avulsion tear (defined as meniscus posterior horn root avulsion or full thickness tear within 9 mm of the root attachment)
  • Age 18-65
  • Ligament injury with concomitant reconstruction is acceptable
  • Malalignment with corrective osteotomy is acceptable

Exclusion criteria

  • Subchondral collapse on pre-op MRI
  • Extrusion greater than 3 mm
  • Intra-op Outerbridge grade 3 or greater chondromalacia
  • Intra-op poor quality meniscus tissue
  • Mal-alignment greater than 5 degrees without corrective osteotomy
  • Obesity with BMI over 40
  • Kellgren Lawrence > grade 2
  • Worker's compensation status

Treatment and study plan

Transtibial pullout technique

Procedure

Evaluating radographs

Primary outcomes

  1. Change in Tegner activity score

    Time frame: baseline, 2 years

    Tegner activity level scale is a graduated list of activities of daily living, recreation, and competitive sports. The patient is asked to select the level of participation that best describes their current level of activity and that before injury. The score varies from 0-10.

    A score of 0 represents sick leave or disability pension because of knee problems, whereas a score of 10 corresponds to participation in national and international elite competitive sports >6 score can only be achieved if the person participates in recreational or competitive sport.

Sponsors and collaborators

Lead sponsor

Mayo Clinic

Other

Registry information

Official study title

Multi-Center Prospective Clinical and Radiographic Outcomes of Meniscus Root Repair Using a Transtibial Pullout Technique

Important dates

Study start
2017
Primary completion
2027
Study completion
2027
First posted
Jan 31, 2017
Registry last updated
Jan 7, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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