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Completed

NCT Number: NCT02504450

Outcomes of Antipsychotic Medication Used in the Emergency Department

To review records of patients treated with antipsychotics (including Adasuve, Geodon, Haldol) in order to evaluate outcomes.

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Key information

Conditions

Agitation,Psychomotor Aberrant Motor Behavior in Dementia Behavior Behavioral Symptoms Dyskinesias Mental Disorders Nervous System Diseases Neurobehavioral Manifestations Neurologic Manifestations Pathological Conditions, Signs and Symptoms Psychomotor Agitation Psychomotor Disorders Schizophrenia Schizophrenia Spectrum and Other Psychotic Disorders Signs and Symptoms

Age range

18 year–80 year

Sex eligibility

All sexes

Study type

Observational

About this study

A retrospective chart review will be performed for all patients presenting to the ED with agitation and subsequently given antipsychotic therapy for treatment. Identification of patients will be through chart review of patients presenting with agitation. Data to be recorded include patient age, gender, medical history, time of presentation, time of treatment, co morbidities, use of restraint, time to disposition and patient outcome. Inclusion criteria include all patients over age 18 presenting to the ED with agitation and treated with antipsychotics. No patients will be knowingly excluded from analysis. We will compare resulting outcomes of patients treated for agitation to see if Adasuve is superior to other commonly prescribed antipsychotics through its rate of discharge home and overall time in the emergency department.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • All patients given antipsychotic therapy for acute agitation

Exclusion criteria

  • None

Treatment and study plan

Adasuve

Drug

Inhaled medication to treat acute agitation in the emergency department

Other names: Loxapine

Alternative medications

Drug

Medication given to treat acute agitation in the emergency department

Other names: Haloperidol, Serenace, Peridol, Haldon, Geodon, Ziprasidone

Primary outcomes

  1. Length of stay in the emergency department

    Time frame: Participants will be followed for the duration of emergency department stay, an expected average of 12 hours.

    We will compare resulting outcomes of patients treated for agitation to see if Adasuve is superior to other commonly prescribed antipsychotics through its rate of discharge home and overall time in the emergency department.

Secondary outcomes

  1. Disposition

    Time frame: Participants will be followed for the duration of emergency department stay, an expected average of 12 hours.

    disposition (home, transfer, admit), and time to disposition

Sponsors and collaborators

Lead sponsor

Wake Forest University Health Sciences

Other

Registry information

Official study title

Outcomes of Antipsychotic Medication Use in the Emergency Department: A Retrospective Comparison Study

Acronym: OAMED

Important dates

Study start
2015
Primary completion
2016
Study completion
2016
First posted
Jul 22, 2015
Registry last updated
Oct 4, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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