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NCT Number: NCT06592469

Outcome of URS in Fresh Versus Recurrent Cases of Stone Ureter

Comparison of Ureteroscopy in fresh versus recurrent cases of stone ureter

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Key information

Sex eligibility

All sexes

Study type

Observational

Primary location

Faculty of Medicine Assiut University

Asyut, Egypt

About this study

Urolithiasis is a common cause of both urology outpatient clinic and emergency room encounters. Approximately 75-90% of ureteral stones pass spontaneously. from this point of view other managements of ureteric stones either ESWL, ureteroscopy or open surgery according to location, site, size, and density. Ureteroscopy is commonly used to diagnose and treat kidney and ureteral stones, ureteral strictures, and urothelial cancers. Semirigid URS is the gold standard of treatment for ureteral stones. High success rates and low morbidity have been reported in semirigid URS. but complications still occur in some cases. The possibility to predict their occurrence should influence patient advisement and better case selection. there are many predictors of successful URS as age, gender, previous ESWL, and stone character. In addition, the impacted stone is a risk factor, and it is described in the literature as ureteral wall thickness, higher grades of hydronephrosis, ureteral stricture, polyp, inflammatory reaction, and difficulty to introduce the guide wire. the literature is very poor in illustrating the previous procedures as a predictor of successful URS only seen in very few original articles as second-time URS after any procedure decreases the rate of success, so it is a point of research that Amr Moustafa aims to clarify. Amr Moustafa will conduct a prospective study to evaluate the outcomes of URS for stones in the fresh and recurrent cases.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • • all cases with middle and lower ureteric stone candidate for endoscopy.
  • Stone 15mm or less.

Exclusion criteria

  • • Patients with a ureteral stent.
  • Patient refusing participation.
  • Pregnant woman.
  • Active urinary tract infection.
  • Comorbidities prevent intervention including bleeding tendency or uncorrectable coagulation profile.

Treatment and study plan

Ureteroscopy

Procedure

URS is done to each group to reveal outcome of stone free rate in fresh versus recurrent cases of stone ureter

Other names: URS

Primary outcomes

  1. Stone free rate of Urereroscopy in fresh versus recurrent cases of stone ureter

    Time frame: 1 day post operative by MSCTKUB or Plain KUB to determine residual stones post operative

    • Stone free rate with a mean operative time of 1 hr by MSCTKUB or Plain KUB to determine residual stones post operative

Secondary outcomes

  1. • Rate of intraoperative findings in each group.

    Time frame: Intraoperative

    • Rate intraoperative findings in each group by ureteroscope
  2. • The rate of complication in each group

    Time frame: Intraoperative by ureteroscope and one day post operative by MSCT

    To determine rate of intraoperative complications as bleeding , ureteric perforation , residual stones

  3. • The rate of stone impaction in each group

    Time frame: Intraoperative by ureteroscope

    Rate of stone impaction in each group fresh and recurrent cases

Study contacts

Contact information is provided by the study sponsor or research team.

Amr Moustafa Hussein Soliman, Resident dr

CONTACT

[email protected]

+201140340697

Sponsors and collaborators

Lead sponsor

Assiut University

Other

Registry information

Official study title

The Outcome of Ureteroscopy in Fresh Versus Recurrent Cases of Stone Ureter (Post-ESWL, Endoscopy, or Open Surgery)

Important dates

Study start
2024
Primary completion
2025
Study completion
2025
First posted
Sep 19, 2024
Registry last updated
Sep 19, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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