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OpenTrials
Completed

NCT Number: NCT03686059

Outcome of Omega 3 FA and Punctal Plugs on Ocular Surface Disease

Ocular surface disease is a common adverse effect of systemic isotretinoin therapy.

The investigators consider that punctal plugs and Omega 3 is a good line for treatment of ocular surface disease associated with systemic isotretinoin therapy

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Key information

Conditions

Ocular Surface Disease

Age range

18 year–40 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 4

Primary location

ACDS

Abu Dhabi, 37496, United Arab Emirates

About this study

Subjective and objective evaluation of ocular surface disease was done at baseline ,1 and 3 months of the study .

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • systemic isotretinoin therapy

Exclusion criteria

  • systemic or ocular diseases ,previous ocular surgery, corneal pathology and contact lens wearer

Treatment and study plan

OMega 3

Drug

daily intake of 250 mg

Other names: docosahexaenoic acid

punctal plug

Device

punctal plug will be inserted in inferior punctum

Other names: OASIS SOFT PLUG

Primary outcomes

  1. Change in Break up Time at baseline and during the study

    Time frame: 3 months

    fluorescein sodium stripes will be used for measurement of Break up Time in seconds

Sponsors and collaborators

Lead sponsor

Benha University

Other

Registry information

Official study title

Outcome of Concomitant Use of Punctal Plugs and Omeg 3 Fatty Acids on Ocular Surface Disease in Patients Using Systemic Isotretinoin

Important dates

Study start
2018
Primary completion
2019
Study completion
2019
First posted
Sep 26, 2018
Registry last updated
Nov 26, 2019

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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