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Completed

NCT Number: NCT03258827

Outcome of Exercise With a Towel in Elderly With Sarcopenia

As the proportion of older adults increases, elderly-related issues attract more attention. Sarcopenia is one of the popular elderly-related issues. Sarcopenia may induce decreased muscle strength, poor physical activity, even disability and increase rate of hospitalization and mortality. Therefore, we want to figure out the management for decreasing prevalence of sarcopenia in older adults. This trial is planned to perform during 2017/08/01~2017/12/31. We plan to enroll 60 elderlies who are sarcopenia. These patient will be divided into 2 group randomize. Experimental group will be received a set of exercise, composed by warm-up, strengthening training with a towel, cold-down, 60 minutes per time, 3 times per week. Control group will be suggested home-based walking activity. We will evaluate the patient's functional performance three times, before training, after training, post-training for three months, respectively. These results will be analyzed by repeated measure ANOVA.

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Key information

Conditions

Sarcopenia Atrophy Muscular Atrophy Nervous System Diseases Neurologic Manifestations Neuromuscular Manifestations Pathological Conditions, Anatomical Pathological Conditions, Signs and Symptoms Signs and Symptoms

Age range

65 year–85 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Wujia Senior Citizens activity Center of Kaohsiung City Government

Kaohsiung City, 830, Taiwan

About this study

As the proportion of older adults increases, elderly-related issues attract more attention. Sarcopenia is one of the popular elderly-related issues. Skeletal muscle is an important component for sustaining physical activity and storing protein. Protein of skeletal muscle is used as energy substrates in cases of starvation or under stress. As being aging, physical condition degenerates gradually. Older adults usually have multiple chronic diseases. Lesser physical function results in less physical activity. As a result, more muscle mass would be lost. In previous study, after the age of 50 year-old, muscle mass decreases 1-2% per year. The velocity of muscle mass decline increases after the age of 60 year-old. Sarcopenia may induce decreased muscle strength, poor physical activity, even disability and increase rate of hospitalization and mortality. Therefore, we want to figure out the management for decreasing prevalence of sarcopenia in older adults.

Exercise is an important method for preventing sarcopenia. In this study, we intend to design a set of exercise which is easily performed for older adults and also has preventing muscle mass loss effect. Towel is an important tool for exercise.

Duration to execute is during 2017/08/01~2017/12/31. We randomize these 60 older adults into 2 groups (experimental group and control group) and there are 30 older adults in each group. Those older adults are age above 65 year-old, have lower grip strength and slower walking speed. One assistant who doesn't know which group these older adults belonged to would record their basic information and is responsible for the evaluation. We will evaluate the older adults' functional performance three times, before training, after training, post-training for three months, respectively.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • age above 65 y/o
  • low muscle mass (male<7.0 kg/m2, female<5.4kg/m2, tested by Dual energy X-ray Absorptiometry)
  • with or without low grip strength (male< 26 kg, female <18 kg)
  • with or without low walk speed (≤ 0.8 m/s).

Exclusion criteria

  • cognitive impairment or can't follow order appropriately
  • elderlies with medical problems that they can't perform the exercise program

Treatment and study plan

Exercise with a towel

Procedure

Exercise program composes with warm-up, strengthening exercise, cold-down, 60 minutes/time, 3 times/week. A towel is an important tool for exercise. Total duration of the program is 3 months.

Other names: Home-based exercise

Home-based exercise

Procedure

Home-based program focuses on walking activity at fast speed, 3 times/week, 60 minutes/times. The total duration is 3 months.

Primary outcomes

  1. Fat mass

    Time frame: Baseline

    Dual-energy X-ray absorptiometry is used for measuring fat mass.

  2. Fat-free mass

    Time frame: Baseline

    Dual-energy X-ray absorptiometry is used for measuring fat-free mass.

  3. Bone mineral density

    Time frame: Baseline

    Dual-energy X-ray absorptiometry is used for measuring bone mineral density.

  4. Maximal grip strength

    Time frame: Baseline

    Handgrip dynamometer is used for measuring maximal grip strength.

  5. Walking speed

    Time frame: Baseline

    Participants are asked to walk at a comfortable speed to perform 10 meter walk test.

  6. Timed up and go test

    Time frame: Baseline

    At first, the participant sits down. Then the participant would be asked to stand up, walk straight for 3 meters, turn around, go back to the chair and sit down. The duration of whole test would be measured.

  7. Times of stand-up and sit-down within 30 seconds

    Time frame: Baseline

    The participant is asked to cross arm before the chest. The investigator would record the times of stand-up and sit-down within 30 seconds.

  8. 6 minutes walking test

    Time frame: Baseline

    At first, the participant sits down for a rest for 10 minutes. The participant would be asked to walk as longer distance as the participant can within 6 minutes.

  9. Berg balance test

    Time frame: Baseline

    The investigator record scores of 14 items involved in Berg balance test for measuring balance of the old adults.

Secondary outcomes

  1. Fat mass

    Time frame: Change between baseline and 3 month after training

    Dual-energy X-ray absorptiometry is used for measuring fat mass

  2. Fat mass

    Time frame: Change between baseline and 6 month after training

    Dual-energy X-ray absorptiometry is used for measuring fat mass

  3. Fat-free mass

    Time frame: Change between baseline and 3 month after training

    Dual-energy X-ray absorptiometry is used for measuring fat-free mass

  4. Fat-free mass

    Time frame: Change between baseline and 6 month after training

    Dual-energy X-ray absorptiometry is used for measuring fat-free mass

  5. Bone mineral density

    Time frame: Change between baseline and 3 month after training

    Dual-energy X-ray absorptiometry is used for measuring bone mineral density

  6. Bone mineral density

    Time frame: Change between baseline and 6 month after training

    Dual-energy X-ray absorptiometry is used for measuring bone mineral density

  7. Maximal grip strength

    Time frame: Change between baseline and 3 month after training

    Handgrip dynamometer is used for measuring maximal grip strength.

  8. Maximal grip strength

    Time frame: Change between baseline and 6 month after training

    Handgrip dynamometer is used for measuring maximal grip strength.

  9. Walking speed

    Time frame: Change between baseline and 3 month after training

    Participants are asked to walk at a comfortable speed to perform 10 meter walk test.

  10. Walking speed

    Time frame: Change between baseline and 6 month after training

    Participants are asked to walk at a comfortable speed to perform 10 meter walk test.

  11. Timed up and go test

    Time frame: Change between baseline and 3 month after training

    At first, the participant sits down. Then the participant would be asked to stand up, walk straight for 3 meters, turn around, go back to the chair and sit down. The duration of whole test would be measured.

  12. Timed up and go test

    Time frame: Change between baseline and 6 month after training

    At first, the participant sits down. Then the participant would be asked to stand up, walk straight for 3 meters, turn around, go back to the chair and sit down. The duration of whole test would be measured.

  13. Times of stand-up and sit-down within 30 seconds

    Time frame: Change between baseline and 3 month after training

    The participant is asked to cross arm before the chest. The investigator would record the times of stand-up and sitdown within 30 seconds.

  14. Times of stand-up and sit-down within 30 seconds

    Time frame: Change between baseline and 6 month after training

    The participant is asked to cross arm before the chest. The investigator would record the times of stand-up and sitdown within 30 seconds.

  15. 6 minutes walking test

    Time frame: Change between baseline and 3 month after training

    At first, the participant sits down for a rest for 10 minutes. The participant would be asked to walk as longer distance as the participant can within 6 minutes.

  16. 6 minutes walking test

    Time frame: Change between baseline and 6 month after training

    At first, the participant sits down for a rest for 10 minutes. The participant would be asked to walk as longer distance as the participant can within 6 minutes.

  17. Berg balance test

    Time frame: Change between baseline and 3 month after training

    The investigator record scores of 14 items involved in Berg balance test for measuring balance of the old adults.

  18. Berg balance test

    Time frame: Change between baseline and 6 month after training

    The investigator record scores of 14 items involved in Berg balance test for measuring balance of the old adults.

Sponsors and collaborators

Lead sponsor

Chang Gung Memorial Hospital

Other

Registry information

Official study title

Chang Gung Medical Hospital

Important dates

Study start
2017
Primary completion
2018
Study completion
2018
First posted
Aug 23, 2017
Registry last updated
Jul 18, 2018

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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