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Completed

NCT Number: NCT04791657

Outcome of Elderly Patients With Appendicitis

This study aims to evaluate factors that predict 30-day complications after the surgical treatment of appendicitis in elderly patients.

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Key information

Conditions

Appendicitis Acute Appendicitis Cecal Diseases Digestive System Diseases Gastroenteritis Gastrointestinal Diseases Infections Intestinal Diseases Intraabdominal Infections

Age range

65 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Gulhane Training and Research Hospital

Ankara, 06010, Turkey (Türkiye)

About this study

Appendicitis in elderly patients is more challenging due to delayed presentation and higher comorbidities, which is associated with increased postoperative morbidity and mortality. In this study, we aim to investigate the factors that predict 30-day complications after the surgical treatment of appendicitis in elderly patients. Records of patients who underwent appendectomy for appendicitis will be extracted. The primary outcome is 30-day postoperative complications. Independent variables examined include demographics, comorbidities, preoperative laboratory values, pathological findings, and surgical features. Both univariate and multivariate regression will be performed to identify factors associated with postoperative complications.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients aged 65 years and older
  • Patients undergoing appendectomy for acute appendicitis (pathologically confirmed)
  • Patients having complete records of clinical data and postoperative follow-up records

Exclusion criteria

  • Patients younger than 65 years
  • Patients undergoing an appendectomy as part of another major operation or those with appendiceal malignancy
  • Patients who are treated nonoperatively for acute appendicitis

Treatment and study plan

Appendectomy

Procedure

Surgical treatment for appendicitis

Primary outcomes

  1. 30-day postoperative complication rate

    Time frame: 30 days

    The primary clinical outcome of interest is 30-day postoperative complications. The Clavien-Dindo classification will be used to grade postoperative outcomes and complications

Secondary outcomes

  1. In-hospital mortality rate

    Time frame: 30 days

    In-hospital mortality is defined as death occurring during the hospital stay after the surgical procedure

  2. 30-day readmission rate

    Time frame: 30 days

    30-day readmission is defined as unplanned readmission to the hospital within 30 days of discharge.

Sponsors and collaborators

Lead sponsor

Gulhane Training and Research Hospital

Other Gov

Registry information

Official study title

Factors Associated With Postoperative Complications After the Surgical Treatment of Appendicitis in Elderly Patients

Important dates

Study start
2017
Primary completion
2020
Study completion
2020
First posted
Mar 10, 2021
Registry last updated
Mar 10, 2021

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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