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Completed

NCT Number: NCT06883474

Osteosclerotic Changes on CT Predict Survival in Prostate Cancer

The study specifically investigated PC patients with bone metastasis and conducted a comprehensive analysis of the correlation between OCs and patient survival outcomes.

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Key information

Conditions

Prostate Cancer (Adenocarcinoma) Adenocarcinoma Carcinoma Genital Diseases Genital Diseases, Male Genital Neoplasms, Male Male Urogenital Diseases Neoplasms Neoplasms by Histologic Type Neoplasms by Site Neoplasms, Glandular and Epithelial Prostate Cancer Metastatic Disease Prostatic Diseases Prostatic Neoplasms Urogenital Diseases Urogenital Neoplasms

Sex eligibility

Male

Study type

Observational

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • 1）Histopathological confirmation of prostate adenocarcinoma
  • 2）Radiologically verified bone metastasis, assessed through bone scintigraphy and CT imaging from the initiation of systemic therapy until disease progression.

Exclusion criteria

  • 1）Lacking of complete clinical profiles.

Treatment and study plan

Osteosclerotic Changes on Computed Tomography

Other

Osteosclerotic Changes on Computed Tomography

Primary outcomes

  1. Radiographic progression-free survival

    Time frame: From enrollment to the end of treatment at 5 years

Secondary outcomes

  1. overall survival

    Time frame: From enrollment to the end of treatment at 5 years

Sponsors and collaborators

Lead sponsor

Sun Yat-sen University

Other

Registry information

Official study title

Osteosclerotic Changes on Computed Tomography Predict Disease Progression and Poor Survival in Prostate Cancer

Important dates

Study start
2010
Primary completion
2023
Study completion
2023
First posted
Mar 19, 2025
Registry last updated
Mar 21, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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