Skip to main content
OpenTrials
Completed

NCT Number: NCT01323894

Osteogenic Effects in Human Mesenchymal Stem Cells Enhanced by Wnt Signaling

The first year purpose:

The best concentration of canonical Wnt3a will be investigated in promoting the osteoblastogenesis of human mesenchymal stem cells.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Primary Disease

Age range

10 year–80 year

Sex eligibility

All sexes

Study type

Observational

Primary location

China Medical Universty Hospital

Taichung, 404, Taiwan

About this study

Our previous work is investigating the viral (Adv-BMP-2) administration for the development of a model to generate bones for possible use in clinical settings; the non-viral and viral administrations will be compared for best osteogenesis effects.

The first year purpose:

The best concentration of canonical Wnt3a will be investigated in promoting the osteoblastogenesis of human mesenchymal stem cells.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • age above 10 years old
  • The patients require surgery ner iliac or abdomen areas

Exclusion criteria

  • age below 10 years old

Treatment and study plan

Primary outcomes

  1. Osteogenic Effects in Human Mesenchymal Stem Cells Enhanced by Wnt Signaling/Hydroxyapatite Nanoparticles--Comparisons between Non-viral and Viral administration in Tissue Engineered Bone Regeneration

    Time frame: 2 years

    August 2011-July 2013

Sponsors and collaborators

Lead sponsor

China Medical University Hospital

Other

Registry information

Official study title

Osteogenic Effects in Human Mesenchymal Stem Cells Enhanced by Wnt Signaling/Hydroxyapatite Nanoparticles--Comparisons Between Non-viral and Viral Administration in Tissue Engineered Bone Regeneration

Important dates

Study start
2011
Primary completion
2012
Study completion
2013
First posted
Mar 28, 2011
Registry last updated
Jun 17, 2016

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.