Organization in Acute Atrial Fibrillation Post Open Heart Surgery

A form of irregular heart rate called, Atrial Fibrillation (AF) is a major clinical problem. It afflicts about 2 million Americans and is the single largest heart related cause of stroke. However, despite 120 years of speculation and research, the mechanisms that cause AF are poorly understood. Acute AF is also the most common irregular heart rate after open-heart surgery in patients. This is seen in as many as 30% of such patients and often results in a longer hospital stay.

In this study we would like to study the pattern of atrial fibrosis (scar tissue in the heart) and an associated blood marker (a protein called pro-collagen-1) in those patients concurrently having open heart surgery.

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Key information

Conditions

Atrial Fibrillation Arrhythmias, Cardiac Cardiovascular Diseases Heart Diseases Pathologic Processes Pathological Conditions, Signs and Symptoms

Age range

18 year–79 year

Sex eligibility

All sexes

Study type

Observational

Primary location

SUNY Upstate Medical University

Syracuse, New York, 13210, United States

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

18 years of age, Male or Female
Able to provide consent
Cardiac surgery, CABG of Valve replacement or repair.

Exclusion criteria

If AF terminates within 1 hour of initiation.
If the patient undergoes electrical cardioversion and/or receives digitalis within the first hour of inclusion.
If the patients and/or their family or the primary caregiver choose to be excluded from the study anytime, even after the initial 24-hour period.
If the patient expires within 1 hour of inclusion into the study. -

Sponsors and collaborators

Lead sponsor

State University of New York - Upstate Medical University

Other

Registry information

Acronym: A-Fib

Important dates

Study start: 2008
Primary completion: 2009
Study completion: 2009
First posted: Feb 13, 2008
Registry last updated: Oct 20, 2021

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed