ODU Human Performance Laboratory
Norfolk, Virginia, 23529, United States
NCT Number: NCT06242015
There is well documented evidence that ingesting dietary carbohydrate in large amounts tends to increase postprandial glucose. In healthy populations, this is not necessarily a problem, but continuous exposure to high levels of glucose-hyperglycemia-is a defining characteristic and risk factor for type 2 diabetes mellitus. Consuming a carbohydrate-rich food as the final food in a meal sequence has been shown to significantly reduce postprandial glucose excursions in both diabetes patients and in healthy controls. The exact mechanisms behind this phenomenon are not well understood, but one proposed course is simply that the vegetable and protein already being digested slows the rate of glucose rise.
Despite the findings, little-to-no research has examined how manipulating the order of foods in a meal impacts subsequent exercise responses. In this experimental crossover study, each participant will undergo two acute feeding conditions (carbohydrate-rich foods first vs. last in a meal), which will be followed by exercise 60 minutes later. We will observe the effects of meal order on postprandial glucose, substrate/fuel utilization, and subjective perceptions at rest and during 30 minutes of exercise.
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Notify Me18 year–60 year
All sexes
Interventional
Not applicable
Norfolk, Virginia, 23529, United States
Healthy volunteers accepted: Yes
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
Rice (150 grams) eaten first, followed by broccoli (150 grams) and chicken (100 grams)
Broccoli (150 grams) and chicken (100 grams) eaten first, followed by rice (150 grams)
Time frame: 2 hours (premeal and 30, 60, 90, and 120 minutes after eating)
Blood glucose will be measured with fingerstick samples and a portable glucometer
Time frame: 100 minutes (premeal and continuously for 90 minutes after eating)
Carbohydrate utilization will be estimated from respiratory gas exchange
Time frame: 100 minutes (premeal and continuously for 90 minutes after eating)
fat utilization will be estimated from respiratory gas exchange
Time frame: 2 hours (Premeal and at 15, 30, 45, 60, 68, 78, 88, 120 minutes after eating)
Hunger, appetite, satiety, and fullness on a 0-10 Likert scale
Time frame: 30 minutes (at 8, 18, 28 minutes of exercise)
Rating of effort during 30-minute exercise bout
Old Dominion University
Other
The Effect of Ordered Eating on Postprandial Glucose and Substrate Utilization During an Acute Exercise Bout
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